Investigation on maintenance hemodialysis patients with mineral and bone disorder in Anhui province, China

• Published in: International urology and nephrology 2023-02, Vol.55 (2), p.389-398
• Main Authors: Tao, Shuman, Li, Xiuyong, Liu, Zhi, Bai, Youwei, Qian, Guangrong, Wu, Han, Li, Ji, Guo, Yuwen, Yang, Shanfei, Chen, Lei, Yang, Jian, Han, Jiuhuai, Ma, Shengyin, Yang, Jing, Yu, Linfei, Shui, Runzhi, Jin, Xiping, Wang, Hongyu, Zhang, Fan, Chen, Tianhao, Li, Xinke, Zong, Xiaoying, Liu, Li, Fan, Jihui, Wang, Wei, Zhang, Yong, Shi, Guangcai, Wang, Deguang
• Format: Article
• Language: English
• Subjects: Bone Diseases; Calcium; Calcium phosphates; China - epidemiology; Chronic Kidney Disease-Mineral and Bone Disorder - epidemiology; Chronic Kidney Disease-Mineral and Bone Disorder - etiology; Comorbidity; Female; Hemodialysis; Hemoglobin; Humans; Kidney diseases; Male; Medicine; Medicine & Public Health; Middle Aged; Minerals; Nephrology; Nephrology - Original Paper; Parathyroid Hormone; Phosphorus; Renal Dialysis - adverse effects; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - therapy; Risk factors; Urology
• ISSN: 1573-2584; 0301-1623; 1573-2584
• DOI: 10.1007/s11255-022-03328-9

Background Chronic kidney disease-mineral bone disorder (CKD-MBD) is a common comorbidity in patients with CKD. The study aims to describe the control rates of serum-corrected calcium (Ca), phosphate (P) and intact parathyroid hormone (iPTH) and its risk factors among maintenance hemodialysis (MHD) patients in Anhui Province of China. Methods The study was conducted in 27 hemodialysis centers of Anhui Province between January 1st 2020 and December 31th 2020. Chi-square test was used to compare the control rates of serum-corrected Ca, P and iPTH between the present study and DOPPS 4 or Anhui Province in 2014. Binary logistic regression analysis was used to explore the risk factors of the control rates of serum-corrected Ca, P and iPTH. Results A total of 3 025 MHD patients were recruited in this study, with a mean age of 54.8 (SD: 12.8) years, and 60.1% were males. According to the Chinese Diagnosis and Treatment Guidelines for CKD-MBD, the control rates of serum-corrected Ca, P and iPTH in the present study were 57.9%, 20.0% and 56.0%, respectively. Based on KDOQI guidelines (2003), the control rates of the above indicators were 43.1%, 35.3% and 22.3%, respectively. The control rates of serum-corrected Ca, P and iPTH in this study were lower than those of DOPPS 4 ( P