Changes in body weight and serum cholesterol after heart transplant in relation to ventricular assist device implantation

Weight gain is common after implantation of a ventricular assist device (VAD) prior to heart transplantation, but post-transplant changes in weight and also in blood lipids in those with VAD is virtually unknown. This study aimed to determine the influence of pre-transplant VAD implantation on body...

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Bibliographic Details
Published in:International journal of artificial organs 2022-12, Vol.45 (12), p.1037-1041
Main Authors: Miura, Kyoko, Yu, Regina, Entwistle, Timothy R, McKenzie, Scott C, Green, Adèle C
Format: Article
Language:English
Subjects:
Blood
Body weight
Body weight gain
Cholesterol
Heart transplantation
Heart transplants
Implantation
Lipids
Medical records
Transplantation
Triglycerides
Ventricle
Ventricular assist devices
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Summary:Weight gain is common after implantation of a ventricular assist device (VAD) prior to heart transplantation, but post-transplant changes in weight and also in blood lipids in those with VAD is virtually unknown. This study aimed to determine the influence of pre-transplant VAD implantation on body weight, blood cholesterol and triglyceride levels in Australian adult heart transplant recipients (HTRs), 1990–2017, from time of transplantation to 36 months post-transplantation. Information on VAD implantation, weight and blood lipids was collected for HTRs from medical records. Changes in weight and blood lipids from post-transplant to 12-, 24 and 36 months later, were assessed by VAD status using linear mixed-effects models. Of 236 heart transplant recipients, 48 (20%) had VAD implants. HTRs irrespective of VAD status, tended to increase their mean weight (p 
ISSN:0391-3988
1724-6040
DOI:10.1177/03913988221118942