Pubic bone ossification at birth in normal and preterm neonates

Of the 266 neonates screened, four were excluded due to lack of reliable gestational period data (n = 1) or because the pubic bone was outside the field of view on the radiograph (n = 3). According to these results, the absence of pubic bone ossification should be considered as potentially indicativ...

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Bibliographic Details
Published in:Pediatric investigation 2022-01, Vol.64 (1), p.e15252-n/a
Main Authors: Hosokawa, Takahiro, Tanami, Yutaka, Sato, Yumiko, Oguma, Eiji
Format: Article
Language:English
Subjects:
Autopsies
Birth weight
bone dysplasia
Gestational age
Humans
Infant, Newborn
neonate
Neonates
Ossification
Osteogenesis
Pediatrics
pubic bone
Pubic Bone - diagnostic imaging
Radiography
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Summary:Of the 266 neonates screened, four were excluded due to lack of reliable gestational period data (n = 1) or because the pubic bone was outside the field of view on the radiograph (n = 3). According to these results, the absence of pubic bone ossification should be considered as potentially indicative of an underlying condition even in extremely premature or low-birthweight neonates. Diseases causing abnormality and delay of ossification in the pubic bone include endocrine disorders, chromosomal disorders and bone dysplasia. 4 Computed tomography and magnetic resonance imaging provide more detailed information on both the ossification centers and the unossified cartilage than radiographs. 4,5 These modalities should therefore be used in studies in the future because they may provide more detailed information about the pubic bone than radiography. 4,5 In conclusion, despite the small number of extremely premature neonates, even in such extremely premature or low-birthweight neonates, the absence of pubic bone ossification in radiographs obtained at birth should be considered potentially indicative of an underlying condition.
ISSN:1328-8067
2096-3726
1442-200X
2574-2272
DOI:10.1111/ped.15252