Early Life Determinants of Vascular Structure in Fetuses, Infants, Children, and Adolescents: A Systematic Review and Meta-Analysis

To investigate the association between early life exposures during the first 1000 days (conception to age 24 months) and aortic intima-media thickness (aIMT), an early indicator of cardiovascular disease (CVD) risk, in youths. The MEDLINE, Embase, Scopus, CINAHL, and Allied and Complementary Medicin...

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Bibliographic Details
Published in:The Journal of pediatrics 2023-01, Vol.252, p.101-110.e9
Main Authors: Varley, Benjamin J., Nasir, Reeja F., Skilton, Michael R., Craig, Maria E., Gow, Megan L.
Format: Article
Language:English
Subjects:
Adolescent
Aorta - diagnostic imaging
aortic intima-media thickness
Cardiovascular Diseases - epidemiology
Carotid Intima-Media Thickness
Child
early life
Female
Fetal Growth Retardation
Fetus
first 1000 days
Gestational Age
Humans
Infant
Infant, Newborn
Pregnancy
subclinical atherosclerosis
systematic review
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Summary:To investigate the association between early life exposures during the first 1000 days (conception to age 24 months) and aortic intima-media thickness (aIMT), an early indicator of cardiovascular disease (CVD) risk, in youths. The MEDLINE, Embase, Scopus, CINAHL, and Allied and Complementary Medicine databases were searched from inception to July 2021. Eligibility criteria included observational controlled studies in youths aged
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2022.08.033