New School Technology Meets Old School Technique: Intensity Modulated Proton Therapy and Laparoscopic Pelvic Sling Facilitate Safe and Efficacious Treatment of Pelvic Sarcoma

• Published in: Advances in radiation oncology 2022, Vol.7 (6), p.101008-101008
• Main Authors: Gits, Hunter C, Dozois, Eric J, Houdek, Matthew T, Ho, Thanh P, Okuno, Scott H, Guenzel, Rachael M, McGrath, Laura A, Kraling, Alan J, Johnson, Jedediah E, Lester, Scott C
• Format: Report
• Language: English
• ISSN: 2452-1094; 2452-1094
• DOI: 10.1016/j.adro.2022.101008

PurposeSmall bowel tolerance may be dose-limiting in the management of some pelvic and abdominal malignancies with curative-intent radiation therapy. Multiple techniques previously have been attempted to exclude the small bowel from the radiation field, including the surgical insertion of an absorbable mesh to serve as a temporary pelvic sling. This case highlights a clinically meaningful application of this technique with modern radiation therapy. Methods and MaterialsA patient with locally invasive, unresectable high-grade sarcoma of the right pelvic vasculature was evaluated for definitive radiation therapy. The tumor immediately abutted the small bowel. The patient underwent laparoscopic placement of a mesh sling to retract the abutting small bowel and subsequently completed intensity modulated proton therapy. ResultsThe patient tolerated the mesh insertion procedure and radiation therapy well with no significant toxic effects. The combination approach achieved excellent dose metrics, and the patient has no evidence of progression 14 months out from treatment. ConclusionsThe combination of mesh as a pelvic sling and proton radiation therapy enabled the application of a curative dose of radiation therapy and should be considered for patients in need of curative-intent radiation when the bowel is in close proximity to the target.