National burden of achondroplasia: an analysis of the National Inpatient and Nationwide Ambulatory Surgery Samples

To estimate the cost of US hospital admissions and outpatient surgeries associated with achondroplasia. Using 2017 data from nationally representative databases, this study identifies hospital admissions and outpatient encounters with an achondroplasia diagnosis. Descriptive measures are reported. T...

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Bibliographic Details
Published in:Journal of comparative effectiveness research 2022-10, Vol.11 (15), p.1135-1146
Main Authors: Broder, Michael S, Chen, Er, Yan, Jessie T, Chang, Eunice, Tarbox, Marian H, Larkin, Adelpha Abrahamson, White, Klane K
Format: Article
Language:English
Subjects:
achondroplasia
hospitalization costs
National Ambulatory Surgery Sample
Nationwide Inpatient Sample
surgery
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Summary:To estimate the cost of US hospital admissions and outpatient surgeries associated with achondroplasia. Using 2017 data from nationally representative databases, this study identifies hospital admissions and outpatient encounters with an achondroplasia diagnosis. Descriptive measures are reported. There were 1985 achondroplasia admissions nationwide. The most frequent admissions were neonatal care (33.7%) in children and musculoskeletal (22.7%) in adults. Average hospital length of stay was 6.8 days, 2.2 days longer than the US mean. Total mean inpatient costs were US$19,959, $7789 greater than the US mean. In the outpatient setting, children 5–14 years accounted for 56.9% of procedures. Achondroplasia is a serious condition with a wide range of lifelong complications frequently requiring hospitalization and surgical intervention.
ISSN:2042-6305
2042-6313
DOI:10.2217/cer-2021-0250