Being born small for gestational age (SGA) might be associated with a higher reoperation rate in proximal hypospadias

Being born small for gestational age (SGA) is associated with a higher frequency and more severe forms of hypospadias as well as with potential developmental differences. This study aims to characterize operative outcomes in SGA boys compared to boys born with normal weight and length for gestationa...

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Published in:Journal of pediatric urology 2022-10, Vol.18 (5), p.609.e1-609.e11
Main Authors: Haid, Bernhard, Tack, Lloyd J.W., Spinoit, Anne-Françoise, Weigl, Chiara, Steinkellner, Lukas, Gernhold, Christa, Banuelos, Beatriz, Sforza, Simone, O'Kelly, Fardod, Oswald, Josef
Format: Article
Language:English
Subjects:
Female
Fetal Growth Retardation - surgery
Gestational Age
Humans
Hypospadias
Hypospadias - pathology
Hypospadias - surgery
Infant
Male
Penis - pathology
Postoperative complications
Reoperation - methods
Small for gestational age
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Summary:Being born small for gestational age (SGA) is associated with a higher frequency and more severe forms of hypospadias as well as with potential developmental differences. This study aims to characterize operative outcomes in SGA boys compared to boys born with normal weight and length for gestational age (appropriate/large for gestational age, AGA/LGA). Demographic data, hypospadias characteristics, associated pathologies and operative outcomes of boys who underwent hypospadias repair at a single center (10/2012–10/2019) were evaluated. Boys were categorized into SGA and non-SGA, which were then compared using unpaired t-tests and chi square tests. To examine the effect of SGA on reoperative risk, a logistic regression model was applied integrating surgical technique, meatal localization and complex hypospadias (narrow glans/plate, curvature, micropenis, bilateral cryptorchidism). SGA boys accounted for 13.7% (n = 80) of the total cohort (n = 584) and 33% of all proximal hypospadias (n = 99, SGA vs. non-SGA 41.3% vs. 13%, p 
ISSN:1477-5131
1873-4898
DOI:10.1016/j.jpurol.2022.08.014