Bisphenol determination in UHT milk and packaging by paper spray ionization mass spectrometry

• Published in: Food chemistry 2023-01, Vol.400, p.134014-134014, Article 134014
• Main Authors: Almeida Soares, Daniel de, Pereira, Igor, Carlos Pereira Sousa, Jean, Alves Bernardo, Ricardo, Costa Simas, Rosineide, Gontijo Vaz, Boniek, Rodrigues Chaves, Andréa
• Format: Article
• Language: English
• Subjects: bisphenol; packaging cartons; paper spray ionization; UHT milk
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2022.134014

•- Paper spray ionization mass spectrometry was used to determine BPA and BPS in UHT milk and milk packaging.•- The protocol is simple and requires minimal sample preparation steps.•- Linearity, LOD, LOQ, precision, and recovery were evaluated.•- Bisphenols were detected in all samples. This study evaluates the use of paper spray ionization mass spectrometry (PSI-MS) for rapid determination of bisphenol A (BPA) and bisphenol S (BPS) in UHT milk and milk packaging. The packages were analyzed by cutting the cartons into triangular shapes and submitting them to PSI-MS analysis. The milk samples were subjected to a simple liquid-liquid extraction and the supernatant was deposited onto a triangular paper that was subsequently used for PSI-MS analysis. In milk, BPS and BPA levels ranged from 60.0 to 150.8 ng mL–1. The LOD and LOQ values were 1.5 and 4.8 ng mL–1 for BPA, and 4.8 and 16.0 ng mL–1 for BPS, respectively. Linearity was R2>0.98 for both compounds. Precision values were below 20%, and recoveries close to 100%. The PSI-MS can be used as a simple, rapid, and accurate methodology to determine bisphenols in milk and milk packaging.