Customized three dimensional printed prosthesis as a novel intercalary reconstruction for resection of extremity bone tumours: a retrospective cohort study

• Published in: International orthopaedics 2022-12, Vol.46 (12), p.2971-2981
• Main Authors: Zhang, Zhao, Shi, Yubo, Fu, Jun, Liu, Dong, Zhu, Dongze, Liu, Xincheng, Dang, Jingyi, Fan, Hongbin
• Format: Article
• Language: English
• Subjects: Artificial Limbs; Bone Neoplasms - pathology; Bone Neoplasms - surgery; Extremities - surgery; Humans; Limb Salvage - methods; Medicine; Medicine & Public Health; Original Paper; Orthopedics; Postoperative Complications - surgery; Retrospective Studies
• ISSN: 0341-2695; 1432-5195
• DOI: 10.1007/s00264-022-05559-y

Aims The 3D-printed prosthesis (3DP) is a novel treatment for massive bone defect reconstruction after tumor resection. This study was aiming to explore the clinical efficacy of customized 3DP for intercalary reconstruction by comparing the clinical outcomes after implanting customized 3DP or conventional allograft in limb salvage surgery. Methods A total of 28 patients with extremity bone tumors who underwent customized 3DP or conventional allograft reconstruction between 2011 and 2018 at our institution were analyzed retrospectively. Among them, 14 cases received customized 3DP reconstruction (3DP group), and 14 cases received conventional allograft reconstruction (control group). Demographics, surgical outcomes, radiographical assessments, limb functions, and post-operative complications between these two groups were collected to evaluate clinical outcomes. Results No significant difference was observed in the demographics, mean intra-operative blood loss, MOSI scores, and MSTS scores between the two groups. Patients in 3DP group had a shorter operative time (157.9 vs 199.6 min, p  = 0.03) and lesser number of fluoroscopy (4.1 vs 8.1, p