The crucial role of LncRNA MIR210HG involved in the regulation of human cancer and other disease

Long noncoding RNAs (lncRNAs) have evoked considerable interest in recent years due to their critical functions in the regulation of disease processes. Abnormal expression of lncRNAs is found in multiple diseases, and lncRNAs have been exploited for diverse medical applications. The lncRNA MIR210HG...

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Bibliographic Details
Published in:Clinical & translational oncology 2023-01, Vol.25 (1), p.137-150
Main Authors: Lu, Juan, Zhu, Danhua, Zhang, Xiaoqian, Wang, Jie, Cao, Hongcui, Li, Lanjuan
Format: Article
Language:English
Subjects:
Gene Expression Regulation, Neoplastic
Humans
Medicine
Medicine & Public Health
Neoplasms - genetics
Oncology
Prognosis
Review Article
RNA, Long Noncoding - genetics
RNA, Long Noncoding - metabolism
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Summary:Long noncoding RNAs (lncRNAs) have evoked considerable interest in recent years due to their critical functions in the regulation of disease processes. Abnormal expression of lncRNAs is found in multiple diseases, and lncRNAs have been exploited for diverse medical applications. The lncRNA MIR210HG is a recently discovered lncRNA that is widely dysregulated in human disease. MIR210HG was described to have biological functions with potential roles in disease development, including cell proliferation, invasion, migration, and energy metabolism. And MIR210HG dysregulation was confirmed to have promising clinical values in disease diagnosis, treatment, and prognosis. In this review, we systematically summarize the expression profiles, roles, underlying mechanisms, and clinical applications of MIR210HG in human disease.
ISSN:1699-3055
1699-3055
DOI:10.1007/s12094-022-02943-3