The role of the neutrophil-to-lymphocyte ratio in avoiding negative appendectomies

The neutrophil-to-lymphocyte ratio (NLR) is an inflammatory biomarker that is easily calculated with data from the differential white blood cell count. The aim of our study was to analyse the role of the NLR in the detection of negative appendectomies and to compare its usefulness with other clinica...

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Bibliographic Details
Published in:Anales de Pediatría 2023-01, Vol.98 (1), p.12-18
Main Authors: Delgado-Miguel, Carlos, Muñoz-Serrano, Antonio, San Basilio, María, Miguel-Ferrero, Miriam, de Ceano-Vivas, María, Martínez, Leopoldo
Format: Article
Language:English
Subjects:
Apendicetomía negativa
Apendicitis
Appendectomy
Appendicitis
Appendicitis - diagnosis
Appendicitis - surgery
Children
Humans
Inflammation - pathology
Lymphocytes
Negative appendectomy
Neutrophil-to-lymphocyte ratio
Neutrophils
Niños
Retrospective Studies
Índice neutrófilo-linfocito
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Summary:The neutrophil-to-lymphocyte ratio (NLR) is an inflammatory biomarker that is easily calculated with data from the differential white blood cell count. The aim of our study was to analyse the role of the NLR in the detection of negative appendectomies and to compare its usefulness with other clinical, sonographic and laboratory factors previously described. We conducted a retrospective study in patients aged less than 16 years who underwent appendectomy in our hospital between 2017 and 2020. We divided patients into 2 groups based on appendiceal histological findings: NA group (negative appendicitis: absence of appendiceal inflammation) and PA group (positive appendicitis: presence of inflammation in any layer of the appendiceal wall). We analysed demographic, clinical, sonographic and laboratory characteristics. We included a total of 1269 patients, 1244 in the PA group and 25 in the NA group, with no differences between groups in demographic characteristics. The proportion of patients that presented with nausea and vomiting was significantly smaller in the NA group compared to the PA group (P 
ISSN:2341-2879
2341-2879
DOI:10.1016/j.anpede.2022.08.005