Morbidity and Mortality of Non-pancreatectomy operations for pancreatic cancer: An ACS-NSQIP analysis

Patients with pancreas cancer may undergo palliative gastrointestinal or biliary bypass. Recent comparisons of post-operative outcomes following such procedures are lacking. We analyzed patients undergoing exploration, gastrojejunostomy, biliary bypass or double bypass for pancreatic cancer using da...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of surgery 2023-02, Vol.225 (2), p.315-321
Main Authors: Adams, Alexandra M., Reames, Bradley N., Krell, Robert W.
Format: Article
Language:English
Subjects:
Ascites
Cancer
Cancer surgery
Complications
Double bypass
Endoscopy
Gastrojejunostomy
Hepaticojejunostomy
Humans
Laboratories
Metastasis
Morbidity
Mortality
Palliation
Palliative surgery
Pancreatectomy
Pancreatic cancer
Pancreatic Neoplasms
Pancreatic Neoplasms - surgery
Patients
Postoperative Complications - diagnosis
Postoperative period
Quality control
Quality improvement
Regression analysis
Regression models
Retrospective Studies
Sepsis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Patients with pancreas cancer may undergo palliative gastrointestinal or biliary bypass. Recent comparisons of post-operative outcomes following such procedures are lacking. We analyzed patients undergoing exploration, gastrojejunostomy, biliary bypass or double bypass for pancreatic cancer using data from the 2005–2019 American College of Surgeons National Surgical Quality Improvement Program. We compared 30-day mortality and complications across procedures and over time periods (2005-10, 2011-14, 2015-19) using multivariable regression models. Factors associated with postoperative mortality were identified. Of 43,525 patients undergoing surgery with a postoperative diagnosis of pancreatic cancer, 5572 met inclusion criteria. Palliative operations included 1037 gastrojejunostomies, 792 biliary bypasses, 650 double bypasses, and 3093 explorations. The proportion of biliary and double bypass procedures decreased from 2005-10 to 2015-19. Gastrojejunostomy had higher 30-day mortality rate (11.5%) than other operations (p 
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2022.08.012