Lowering effect of combined sweet potato and onion intake on plasma quercetin concentration and underlying mechanism involving intestinal β-glucosidase activity

A combined intake of cooked sweet potato and fried onion in humans was found to suppress the increase of plasma quercetin metabolite concentration. Experiments using rat β-glucosidase indicated that excess carbohydrate digestion products, especially glucose-containing saccharides, interfere with the...

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2022-11, Vol.86 (12), p.1695-1698
Main Authors: Nuka, Erika, Takahashi, Masako, Okitsu, Masami, Nayama, Chisako, Nishijima, Honomi, Sogawa, Ryutaro, Kawabata, Kyuichi, Terao, Junji, Mukai, Rie
Format: Article
Language:English
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Summary:A combined intake of cooked sweet potato and fried onion in humans was found to suppress the increase of plasma quercetin metabolite concentration. Experiments using rat β-glucosidase indicated that excess carbohydrate digestion products, especially glucose-containing saccharides, interfere with the deglycosylation of quercetin glucosides during intestinal epithelial uptake. Combined meals of sweet potato and onion may lower the bioavailability of onion quercetin glucosides.
ISSN:1347-6947
1347-6947
DOI:10.1093/bbb/zbac155