Required time for pre-oncological dental management – A rapid review of the literature

• Published in: Oral oncology 2022-11, Vol.134, p.106116-106116, Article 106116
• Main Authors: Mazzetti, Thais, Sergio da Silva Santos, Paulo, Spindola Antunes, Héliton, Montagner, Anelise Fernandes, Hélène van de Sande, Françoise, Timm Maske, Tamires
• Format: Article
• Language: English
• Subjects: Chemotherapy; Dental management; Head and Neck cancer; Oral mucositis; Osteoradionecrosis; Radiotherapy; Timelines. Oral Cancer
• ISSN: 1368-8375; 1879-0593
• DOI: 10.1016/j.oraloncology.2022.106116

This study identified the scientific literature comparing the influence of different times in which dental procedures were performed before the oncological treatments (radiotherapy and/or chemotherapy) on the risk of oral complications development. MEDLINE/PubMed and Embase databases were searched, and articles were selected by title, abstract and full-text assessment. The search identified 2,356 articles and three retrospective observational studies were included. Data were collected and analyzed according to the dental procedure, the time before oncological treatment, and oral complications. Risk of bias (ROBINS) and certainty of evidence (GRADE) were evaluated. Pairwise meta-analyses were performed from dental extractions (Exo) data according to the time which were performed and ORN development using a random-effect model (RR and 95 % CI, p  2 weeks before oncological treatment to avoid ORN complications. More studies are needed to conclude the appropriate time to perform dental procedures to decrease other associated oral complications. (CRD42021272652).