Inhaled Nitric Oxide Therapy in the Post-Acute Phase in Extremely Preterm Infants: A Japanese Cohort Study

To determine the trends in inhaled nitric oxide (iNO) utilization in the late phase of hospitalization in a large Japanese cohort of extremely preterm infants and evaluate its benefit on long-term outcomes. This was a retrospective multicenter cohort study of 15 977 extremely preterm infants born at...

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Bibliographic Details
Published in:The Journal of pediatrics 2023-01, Vol.252, p.61-67.e5
Main Authors: Nakanishi, Hidehiko, Isayama, Tetsuya, Kokubo, Masayo, Hirano, Shinya, Kusuda, Satoshi
Format: Article
Language:English
Subjects:
Administration, Inhalation
bronchopulmonary dysplasia
Bronchopulmonary Dysplasia - drug therapy
Cohort Studies
East Asian People
extremely preterm infants
Female
Humans
Infant
Infant, Extremely Premature
Infant, Newborn
Nitric Oxide - therapeutic use
Pregnancy
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Summary:To determine the trends in inhaled nitric oxide (iNO) utilization in the late phase of hospitalization in a large Japanese cohort of extremely preterm infants and evaluate its benefit on long-term outcomes. This was a retrospective multicenter cohort study of 15 977 extremely preterm infants born at
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2022.07.057