Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report

BackgroundNon-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. Case reportA 29-year-old female patient presented with low-grade fev...

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Bibliographic Details
Published in:Annals of medicine and surgery (2012) 2022, Vol.81, p.104449-104449
Main Authors: Khan, Qaisar Ali, Mumtaz, Arif, Baqi, Abdul, Ain, Hoor Ul, Mahfooz, Rabia Salman, Asim, Nowshad, Iram, Sumaira, Hussien Mohamed Ahmed, Khabab Abbasher, Tahir, Muhammad Junaid, Yousaf, Zohaib
Format: Report
Language:English
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Summary:BackgroundNon-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. Case reportA 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy. ConclusionNHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.
ISSN:2049-0801
2049-0801
DOI:10.1016/j.amsu.2022.104449