Efficacy of one-stop endovascular intervention in treatment of left iliac vein compression syndrome complicated with deep venous thrombosis of lower limbs

• Published in: Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban 2022-06, Vol.51 (3), p.341-349
• Main Authors: Jiang, Guangwei, Ding, Dianzhu, Zhang, Xiaoyu, Niu, Shuai, Lyu, Bonan
• Format: Article
• Language: English
• Subjects: Alanine Transaminase; Bilirubin; Creatinine; Humans; Lower Extremity; May-Thurner Syndrome - complications; May-Thurner Syndrome - therapy; Retrospective Studies; Stents - adverse effects; Thrombolytic Therapy - adverse effects; Treatment Outcome; Vascular Patency; Venous Thrombosis - complications; Venous Thrombosis - therapy
• ISSN: 1008-9292
• DOI: 10.3724/zdxbyxb-2022-0121

To evaluate the clinical effect and safety of one-stop endovascular intervention in treatment of left iliac vein compression syndrome (IVCS) complicated with deep venous thrombosis (DVT) of lower limbs. Clinical data of 26 patients with secondary DVT due to IVCS admitted in the Department of Vascular Surgery, Hebei General Hospital from January 2018 to December 2021 were retrospectively analyzed. All patients underwent one-stop endovascular intervention procedure, including ultrasound-guided deep venipuncture, Angiojet catheter aspiration, iliac vein balloon dilation, stent implantation and simultaneous filter retrieval. The operation time and catheter aspiration time were documented; the preoperative and postoperative left lower extremity deep vein venous patency, circumferences of bilateral limbs at 15 cm above the knee and 10 cm below the knee, and the levels of hemoglobin, creatinine, alanine aminotransferase (ALT), aspertate aminotransferase (AST), total bilirubin and indirect bilirubin were measured. The incidence of post-thrombotic syndrome (PTS) and iliac vein stent patency were recorded through follow-up. The one-stop endovascular intervention was successfully performed in 26 patients, with the operation time of (171±35) min and the thrombolysis time of (263±89) s. After treatment, the left lower extremity deep vein venous patency, circumferences of bilateral limbs at 15 cm above the knee and 10 cm below the knee were decreased (all