A randomized split‐face comparative study of long‐pulsed alexandrite plus low‐fluence Nd:YAG laser versus pulsed‐dye laser in the treatment of rosacea

Objectives To compare the effectiveness of long‐pulsed alexandrite laser (LPAL) with that of pulsed‐dye laser (PDL) for rosacea. Methods This was a single‐blind randomized controlled trial on 27 patients who were clinically diagnosed with rosacea. Randomly assigned split face in each patient receive...

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Published in:Lasers in surgery and medicine 2022-11, Vol.54 (9), p.1217-1225
Main Authors: Park, Sujin, Lee, Joo Hee, Kang, Eunji, Kim, Hyun, Kim, Ji Young, Lee, Eun Jung, Bae, Yu Jeong, Kim, Jihee, Oh, Sang Ho
Format: Article
Language:English
Subjects:
Alexandrite
Comparative studies
Dye lasers
Dyes
Erythema
Fluence
Lasers
long pulse alexandrite laser
Nd:YAG laser
Neodymium lasers
Patient satisfaction
Patients
pulse‐dye laser
Reduction
Rosacea
Semiconductor lasers
Skin diseases
YAG lasers
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Summary:Objectives To compare the effectiveness of long‐pulsed alexandrite laser (LPAL) with that of pulsed‐dye laser (PDL) for rosacea. Methods This was a single‐blind randomized controlled trial on 27 patients who were clinically diagnosed with rosacea. Randomly assigned split face in each patient received four times monthly treatment of LPAL plus low‐fluence Nd:YAG with the contralateral side serving as the control treated with PDL. At every visit, the erythema index (EI) was measured with skin analysis systems, and two independent dermatologists evaluated digital photographs for five‐point global aesthetic improvement scale (GAIS). Results The EI significantly decreased on both treated sides (LPAL 366.5 ± 101.0 vs. 295.8 ± 90.2, p 
ISSN:0196-8092
1096-9101
DOI:10.1002/lsm.23605