Selective deuteration of bupropion slows epimerization and reduces metabolism

Saved in:
Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2022-11, Vol.76, p.129009-129009, Article 129009
Main Authors: Shi, Yuanyuan, Dinh, Jean, Pelletier, Robert, Raccor, Brianne, Yusuff, Naeem, Morgan, Adam J., Harbeson, Scott, Uttamsingh, Vinita, Totah, Rheem A.
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593
cites cdi_FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593
container_end_page 129009
container_issue
container_start_page 129009
container_title Bioorganic & medicinal chemistry letters
container_volume 76
creator Shi, Yuanyuan
Dinh, Jean
Pelletier, Robert
Raccor, Brianne
Yusuff, Naeem
Morgan, Adam J.
Harbeson, Scott
Uttamsingh, Vinita
Totah, Rheem A.
description
doi_str_mv 10.1016/j.bmcl.2022.129009
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2720425751</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2720425751</sourcerecordid><originalsourceid>FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593</originalsourceid><addsrcrecordid>eNotkEtLxDAUhYMoOI7-AVddumm9uU0fWcqgjjDiQgV3IY8b6NBOa9Iq-uudUleHAx-Hw8fYNYeMAy9v95npbJshIGYcJYA8YSsuSpHmAopTtgJZQlpL8XHOLmLcA3ABQqzY8yu1ZMfmixJH00hBj01_SHqfmGkI_TCX2PbfMaGh6Sg0vwugDy4J5CZLMelo1KZvm9hdsjOv20hX_7lm7w_3b5ttunt5fNrc7VKLNYypqww3HmqJxuc-x0JiXWopRFVWhZfgsK7BSS2s1qXXtkYhtEEHeY4gC5mv2c2ye7z4OVEcVddES22rD9RPUWGFILCoCn5EcUFt6GMM5NUQmk6HH8VBze7UXs3u1OxOLe7yP4LSZC0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2720425751</pqid></control><display><type>article</type><title>Selective deuteration of bupropion slows epimerization and reduces metabolism</title><source>ScienceDirect Freedom Collection</source><creator>Shi, Yuanyuan ; Dinh, Jean ; Pelletier, Robert ; Raccor, Brianne ; Yusuff, Naeem ; Morgan, Adam J. ; Harbeson, Scott ; Uttamsingh, Vinita ; Totah, Rheem A.</creator><creatorcontrib>Shi, Yuanyuan ; Dinh, Jean ; Pelletier, Robert ; Raccor, Brianne ; Yusuff, Naeem ; Morgan, Adam J. ; Harbeson, Scott ; Uttamsingh, Vinita ; Totah, Rheem A.</creatorcontrib><identifier>ISSN: 0960-894X</identifier><identifier>EISSN: 1464-3405</identifier><identifier>DOI: 10.1016/j.bmcl.2022.129009</identifier><language>eng</language><ispartof>Bioorganic &amp; medicinal chemistry letters, 2022-11, Vol.76, p.129009-129009, Article 129009</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593</citedby><cites>FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Shi, Yuanyuan</creatorcontrib><creatorcontrib>Dinh, Jean</creatorcontrib><creatorcontrib>Pelletier, Robert</creatorcontrib><creatorcontrib>Raccor, Brianne</creatorcontrib><creatorcontrib>Yusuff, Naeem</creatorcontrib><creatorcontrib>Morgan, Adam J.</creatorcontrib><creatorcontrib>Harbeson, Scott</creatorcontrib><creatorcontrib>Uttamsingh, Vinita</creatorcontrib><creatorcontrib>Totah, Rheem A.</creatorcontrib><title>Selective deuteration of bupropion slows epimerization and reduces metabolism</title><title>Bioorganic &amp; medicinal chemistry letters</title><issn>0960-894X</issn><issn>1464-3405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotkEtLxDAUhYMoOI7-AVddumm9uU0fWcqgjjDiQgV3IY8b6NBOa9Iq-uudUleHAx-Hw8fYNYeMAy9v95npbJshIGYcJYA8YSsuSpHmAopTtgJZQlpL8XHOLmLcA3ABQqzY8yu1ZMfmixJH00hBj01_SHqfmGkI_TCX2PbfMaGh6Sg0vwugDy4J5CZLMelo1KZvm9hdsjOv20hX_7lm7w_3b5ttunt5fNrc7VKLNYypqww3HmqJxuc-x0JiXWopRFVWhZfgsK7BSS2s1qXXtkYhtEEHeY4gC5mv2c2ye7z4OVEcVddES22rD9RPUWGFILCoCn5EcUFt6GMM5NUQmk6HH8VBze7UXs3u1OxOLe7yP4LSZC0</recordid><startdate>20221115</startdate><enddate>20221115</enddate><creator>Shi, Yuanyuan</creator><creator>Dinh, Jean</creator><creator>Pelletier, Robert</creator><creator>Raccor, Brianne</creator><creator>Yusuff, Naeem</creator><creator>Morgan, Adam J.</creator><creator>Harbeson, Scott</creator><creator>Uttamsingh, Vinita</creator><creator>Totah, Rheem A.</creator><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20221115</creationdate><title>Selective deuteration of bupropion slows epimerization and reduces metabolism</title><author>Shi, Yuanyuan ; Dinh, Jean ; Pelletier, Robert ; Raccor, Brianne ; Yusuff, Naeem ; Morgan, Adam J. ; Harbeson, Scott ; Uttamsingh, Vinita ; Totah, Rheem A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shi, Yuanyuan</creatorcontrib><creatorcontrib>Dinh, Jean</creatorcontrib><creatorcontrib>Pelletier, Robert</creatorcontrib><creatorcontrib>Raccor, Brianne</creatorcontrib><creatorcontrib>Yusuff, Naeem</creatorcontrib><creatorcontrib>Morgan, Adam J.</creatorcontrib><creatorcontrib>Harbeson, Scott</creatorcontrib><creatorcontrib>Uttamsingh, Vinita</creatorcontrib><creatorcontrib>Totah, Rheem A.</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioorganic &amp; medicinal chemistry letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shi, Yuanyuan</au><au>Dinh, Jean</au><au>Pelletier, Robert</au><au>Raccor, Brianne</au><au>Yusuff, Naeem</au><au>Morgan, Adam J.</au><au>Harbeson, Scott</au><au>Uttamsingh, Vinita</au><au>Totah, Rheem A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Selective deuteration of bupropion slows epimerization and reduces metabolism</atitle><jtitle>Bioorganic &amp; medicinal chemistry letters</jtitle><date>2022-11-15</date><risdate>2022</risdate><volume>76</volume><spage>129009</spage><epage>129009</epage><pages>129009-129009</pages><artnum>129009</artnum><issn>0960-894X</issn><eissn>1464-3405</eissn><doi>10.1016/j.bmcl.2022.129009</doi><tpages>1</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0960-894X
ispartof Bioorganic & medicinal chemistry letters, 2022-11, Vol.76, p.129009-129009, Article 129009
issn 0960-894X
1464-3405
language eng
recordid cdi_proquest_miscellaneous_2720425751
source ScienceDirect Freedom Collection
title Selective deuteration of bupropion slows epimerization and reduces metabolism
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T10%3A49%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Selective%20deuteration%20of%20bupropion%20slows%20epimerization%20and%20reduces%20metabolism&rft.jtitle=Bioorganic%20&%20medicinal%20chemistry%20letters&rft.au=Shi,%20Yuanyuan&rft.date=2022-11-15&rft.volume=76&rft.spage=129009&rft.epage=129009&rft.pages=129009-129009&rft.artnum=129009&rft.issn=0960-894X&rft.eissn=1464-3405&rft_id=info:doi/10.1016/j.bmcl.2022.129009&rft_dat=%3Cproquest_cross%3E2720425751%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c280t-d7b1bf0892bf3f3259286a9447675f90d2880d9a4caa6fac8244ab2d033209593%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2720425751&rft_id=info:pmid/&rfr_iscdi=true