Vitality, mental health and role-physical mediate the influence of coping on depressive symptoms and self-efficacy in patients with non-alcoholic fatty liver disease: A cross-sectional study

• Published in: Journal of psychosomatic research 2022-11, Vol.162, p.111045-111045, Article 111045
• Main Authors: Funuyet-Salas, Jesús, Pérez-San-Gregorio, María Ángeles, Martín-Rodríguez, Agustín, Romero-Gómez, Manuel
• Format: Article
• Language: English
• Subjects: Adaptation, Psychological; Cross-Sectional Studies; Depression - psychology; Diabetes Mellitus; Fibrosis; Humans; Mental Health; Non-alcoholic Fatty Liver Disease - complications; Obesity - complications; Quality of Life; Self Efficacy
• ISSN: 0022-3999; 1879-1360
• DOI: 10.1016/j.jpsychores.2022.111045

Our aim was to determine whether the association between active coping and depressive symptoms in patients with non-alcoholic fatty liver disease (NAFLD) was mediated by vitality, and whether diabetes and obesity could impact on this relationship. We also wanted to find out whether mental health and role-physical modulated the relationship between passive/avoidance coping and self-efficacy, and the role of liver fibrosis. Depressive symptoms (BDI-II), self-efficacy (GSE), coping (COPE-28) and quality of life (SF-12) were evaluated in 509 biopsy-proven NAFLD patients in this cross-sectional study. Mediation and moderated mediation models were conducted using the SPSS PROCESS v3.5 macro. Vitality mediated the relationship between active coping and depressive symptoms (-2.254, CI = -2.792 to -1.765), with diabetes (-0.043, p = 0.017) and body mass index (BMI) (-0.005, p = 0.009) moderating the association. In addition, mental health (-6.435, CI = -8.399 to -4.542) and role-physical (-1.137, CI = -2.141 to -0.315) mediated the relationship between passive/avoidance coping and self-efficacy, with fibrosis stage (0.367, p