Characterization and application of poly(β-hydroxyalkanoates) family as composite biomaterials

Some polyhydroxyalkanoates (PHA), polyhydroxybutyrate (PHB) and copolymers poly(hydroxybutyrate-co-hydroxyvalerate) (P(HB-co-HV)), were characterized by different techniques (GPC, DSC, DMA, FTIR, DRX) in order to be used in hydroxyapatite (HA) composites. These polymers presented high molecular weig...

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Bibliographic Details
Published in:Polymer testing 2000-08, Vol.19 (5), p.485-492
Main Authors: Galego, Norma, Rozsa, Chavati, Sánchez, Rubén, Fung, Juan, Analı́a Vázquez, Santo Tomás, Julio
Format: Article
Language:English
Subjects:
Applied sciences
Biomaterials
Composites
Compressive strength
Copolymers
Crystal structure
Elastic moduli
Exact sciences and technology
Forms of application and semi-finished materials
Fracture fixation
Molecular weight
Phosphate minerals
Polymer industry, paints, wood
Technology of polymers
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Summary:Some polyhydroxyalkanoates (PHA), polyhydroxybutyrate (PHB) and copolymers poly(hydroxybutyrate-co-hydroxyvalerate) (P(HB-co-HV)), were characterized by different techniques (GPC, DSC, DMA, FTIR, DRX) in order to be used in hydroxyapatite (HA) composites. These polymers presented high molecular weights and are semicrystalline materials. The crystallinity has a slight tendency to decrease with the increasing HV content in the copolymer. PHA/HA composites prepared at the same composition, showed a lower elastic modulus than 0 and 8% HV content. The composite P(HB-co-8%HV)/HA (30% w/w) has the highest modulus. In addition, this composite has a mechanical strength in compression of 62 MPa, which is about the same order of magnitude of several human bones and thus it is interesting as biomaterial for use in fracture fixation.
ISSN:0142-9418
1873-2348
DOI:10.1016/S0142-9418(99)00011-2