Is low-level laser therapy effective in the treatment of herpes labialis? Systematic review and meta-analysis

The objective of this systematic review is to evaluate the effectiveness of low-level laser therapy in the treatment of herpes labialis. The searches were carried out independently by 2 researchers and the articles were selected through the electronic databases according to the inclusion and exclusi...

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Bibliographic Details
Published in:Lasers in medical science 2022-12, Vol.37 (9), p.3393-3402
Main Authors: Barros, Ana Waleska Pessoa, Sales, Pedro Henrique da Hora, Silva, Paulo Goberlânio de Barros, Gomes, Ana Claudia Amorim, Carvalho, Alessandra Albuquerque Tavares, Leão, Jair Carneiro
Format: Article
Language:English
Subjects:
Bias
Clinical trials
Dentistry
Effectiveness
Healing
Herpes labialis
Lasers
Medicine
Medicine & Public Health
Meta-analysis
Optical Devices
Optics
Photonics
Quantum Optics
Reduction
Review Article
Systematic review
Therapy
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Summary:The objective of this systematic review is to evaluate the effectiveness of low-level laser therapy in the treatment of herpes labialis. The searches were carried out independently by 2 researchers and the articles were selected through the electronic databases according to the inclusion and exclusion criteria previously established. Initially, 480 articles were found, of which 7 randomized clinical trials and 1 clinical trial were selected. In total, 928 patients were included. In the meta-analysis, the mean healing time for laser use was significant, showing a mean reduction of 1.37 [CI 95% = 0.92 to 1.82] days for tissue healing ( p  
ISSN:1435-604X
0268-8921
1435-604X
DOI:10.1007/s10103-022-03653-6