Clinical Outcomes of Patients with Benign Peptic Ulcer Bleeding After an Emergency Endoscopy Based on Patient Location

• Published in: Digestive diseases and sciences 2023-04, Vol.68 (4), p.1539-1550
• Main Authors: Cha, Boram, Noh, Jin Hee, Ahn, Ji Yong, Lee, Jun Su, Kim, Ga Hee, Na, Hee Kyong, Jung, Kee Wook, Lee, Jeong Hoon, Kim, Do Hoon, Choi, Kee Don, Song, Ho June, Lee, Gin Hyug, Jung, Hwoon-Yong
• Format: Article
• Language: English
• Subjects: Biochemistry; Clinical outcomes; Emergency medical care; Endoscopy; Endoscopy, Gastrointestinal; Gastroenterology; Gastrointestinal Hemorrhage - diagnosis; Gastrointestinal Hemorrhage - etiology; Gastrointestinal Hemorrhage - therapy; Hemostasis, Endoscopic; Hepatology; Humans; Medicine; Medicine & Public Health; Mortality; Oncology; Original Article; Patients; Peptic Ulcer; Peptic Ulcer Hemorrhage - diagnosis; Peptic Ulcer Hemorrhage - therapy; Recurrence; Risk factors; Transplant Surgery; Ulcers
• ISSN: 0163-2116; 1573-2568
• DOI: 10.1007/s10620-022-07708-0

Background and Aims In the efforts toward reducing bleeding-related mortality, it is crucial to determine the risk factors for rebleeding after endoscopic hemostasis in benign peptic ulcer (BPU). Methods Between 2013 and 2017, the medical records of 864 BPU patients were selected from 5076 who had undergone emergency endoscopy for suspected upper gastrointestinal bleeding. Patients who visited the emergency room or were hospitalized for other illnesses were selected. The primary end point was rebleeding within 30 days after initial endoscopy. The risk factors of rebleeding and subgroup analyses according to patient location were evaluated. Results Among 864 BPU bleeding patients, rebleeding after completion of BPU bleeding occurred in 140 (16.2%). Initial indicators of hypotension (OR 1.878, p  = 0.005) and Forrest classes Ia (OR 25.53, p