Lung Transplantation for Multiple Giant Hamartomas: First Case Report and Review of the Literature

• Published in: Transplantation proceedings 2022-11, Vol.54 (9), p.2506-2508
• Main Authors: Fernández-González, Alba María, García, Francisco Javier González, Chávez, David Sebastián Poveda, López, Eloisa Ruiz, Leiva-Cepas, Fernando, Álvarez, Antonio
• Format: Article
• Language: English
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2022.09.008

To assess lung transplant as a solution for a rare complication of giant lung hamartoma, in which surgical resection was discouraged because of severe underlying chronic lung disease. A 54-year-old woman had an episode of severe acute hemoptysis. Imaging techniques showed 2 masses in the right lung as hamartomas and severe pulmonary emphysema. After resolution of the acute episode of hemoptysis, the case could have been solved with a right pneumonectomy; however, a single-lung transplant was performed because of the underlying chronic obstructive pulmonary disease. The outcome of the surgery was satisfactory, although a second operation was required because of bleeding. The patient was discharged and currently has a good quality of life, with no recurrence of the disease. The pathologic anatomy of the surgical specimen confirmed the diagnosis of multiple giant hamartomas. Lung transplant could be a feasible procedure to treat life-threatening complications of benign tumors in selected patients with pulmonary end-stage disease.