Treatment of recurrent high myopic macular hole associated with retinal detachment using a human amniotic membrane

Purpose To determine the efficacy of using a human amniotic membrane to close macular hole retinal detachment in highly myopic eyes. Study design Prospective, consecutive, nonrandomized interventional study. Methods We included 19 high myopic eyes from 19 patients affected by macular hole retinal de...

Full description

Saved in:
Bibliographic Details
Published in:Japanese journal of ophthalmology 2022-11, Vol.66 (6), p.518-526
Main Authors: Caporossi, Tomaso, Governatori, Lorenzo, Gambini, Gloria, Baldascino, Antonio, De Vico, Umberto, Ripa, Matteo, Scampoli, Alessandra, Carlà, Matteo Mario, Rizzo, Clara, Kilian, Raphael, Rizzo, Stanislao
Format: Article
Language:English
Subjects:
Amnion
Amniotic membrane
Angiography
Basement Membrane - surgery
Clinical Investigation
Extracellular matrix
Eye
Humans
Medicine
Medicine & Public Health
Membranes
Myopia, Degenerative - complications
Myopia, Degenerative - diagnosis
Ophthalmology
Prospective Studies
Retina
Retinal detachment
Retinal Detachment - diagnosis
Retinal Detachment - etiology
Retinal Detachment - surgery
Retinal Perforations - diagnosis
Retinal Perforations - etiology
Retinal Perforations - surgery
Retrospective Studies
Tomography, Optical Coherence
Visual Acuity
Vitrectomy - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To determine the efficacy of using a human amniotic membrane to close macular hole retinal detachment in highly myopic eyes. Study design Prospective, consecutive, nonrandomized interventional study. Methods We included 19 high myopic eyes from 19 patients affected by macular hole retinal detachment who had already undergone vitrectomy with internal limiting membrane peeling. The patients underwent vitrectomy with amniotic membrane transplant. Results Primary success was achieved after 3 months in 89.5% (17 of 19 eyes) and final macular hole closure was obtained in 94.7% (18 of 19 eyes) of the patients. The final retinal reattachment rate was 100%. The final 12-month mean BCVA improved from 20/2000 (2 logMAR) to 20/250 (1.1 logMAR). OCT-angiography revealed a high correlation between the superficial and deep capillary plexus and the final BCVA. Conclusion Human amniotic membrane patches can effectively repair macular hole retinal detachment in high myopic eyes in terms of anatomic results and BCVA recovery.
ISSN:0021-5155
1613-2246
DOI:10.1007/s10384-022-00953-w