Posttraumatic Stress Disorder (PTSD) as a Risk Factor for Cardiovascular Disease: Implications for Future Research and Clinical Care

Purpose of Review Posttraumatic stress disorder (PTSD) may be an important risk factor for cardiovascular disease (CVD). We explore the literature linking PTSD to CVD, potential mechanisms, interventions, and clinical implications. We outline gaps in current literature and highlight necessary future...

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Bibliographic Details
Published in:Current cardiology reports 2022-12, Vol.24 (12), p.2067-2079
Main Authors: Hargrave, Anita S., Sumner, Jennifer A., Ebrahimi, Ramin, Cohen, Beth E.
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular Diseases - complications
Humans
Medicine
Medicine & Public Health
Psychological Aspects of Cardiovascular Diseases (IM Kronish
Risk Factors
Section Editor
Stress Disorders, Post-Traumatic - complications
Stress Disorders, Post-Traumatic - therapy
Topical Collection on Psychological Aspects of Cardiovascular Diseases
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Summary:Purpose of Review Posttraumatic stress disorder (PTSD) may be an important risk factor for cardiovascular disease (CVD). We explore the literature linking PTSD to CVD, potential mechanisms, interventions, and clinical implications. We outline gaps in current literature and highlight necessary future research. Recent Findings PTSD has been independently associated with deleterious effects on cardiovascular health through biological, behavioral, and societal pathways. There are evidence-based psychotherapeutic interventions and pharmacotherapies for PTSD that may mitigate its impact on CVD. However, there are limited studies that rigorously analyze the impact of treating PTSD on cardiovascular outcomes. Summary Trauma-informed CVD risk stratification, education, and treatment offer opportunities to improve patient care. These approaches can include a brief validated screening tool for PTSD identification and treatment. Pragmatic trials are needed to test PTSD interventions among people with CVD and evaluate for improved outcomes.
ISSN:1523-3782
1534-3170
DOI:10.1007/s11886-022-01809-y