Ileus rate after abdominal wall reconstruction: a retrospective analysis of two clinical trials

Purpose Postoperative ileus (POI) is the paralytic disruption of gastrointestinal motility, a common complication following abdominal wall reconstruction that often leads to increased patient morbidity and length of stay (LOS). We reviewed two randomized clinical trials to determine POI rates, predi...

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Bibliographic Details
Published in:Hernia : the journal of hernias and abdominal wall surgery 2022-12, Vol.26 (6), p.1591-1598
Main Authors: Greco, C. D., Petro, C. C., Thomas, J. D., Montelione, K., Tu, C., Fafaj, A., Zolin, S., Krpata, D., Rosenblatt, S., Rosen, M., Beffa, L., Prabhu, A.
Format: Article
Language:English
Subjects:
Abdomen
Abdominal Surgery
Abdominal wall
Abdominal Wall - surgery
Body mass index
Clinical trials
Clinical Trials as Topic
Comorbidity
Costs
Gastric motility
Hernia
Herniorrhaphy - adverse effects
Humans
Ileus - etiology
Medicine
Medicine & Public Health
Morbidity
Original Article
Patients
Postoperative Complications - etiology
Regression analysis
Retrospective Studies
Risk Factors
Surgery
Surgical mesh
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Summary:Purpose Postoperative ileus (POI) is the paralytic disruption of gastrointestinal motility, a common complication following abdominal wall reconstruction that often leads to increased patient morbidity and length of stay (LOS). We reviewed two randomized clinical trials to determine POI rates, predictive factors, LOS, and associated cost. Methods Two randomized trials were performed from 2017–2019 with all patients receiving elective open abdominal wall reconstruction with retromuscular mesh. Using multivariate logistic regression, we performed a retrospective analysis including demographics and operative details from patients at a single site to determine predictive factors for POI. All medical costs encompassing surgery and the 30-day postoperative period were compared between ileus and non-ileus groups. Results Four hundred and seventy patients were reviewed with a POI rate of 13.0% ( N  = 61). There were no differences in age, body mass index (BMI), history of abdominal surgery, or comorbidities between patients with and without POI. Logistic regression showed no association with POI and age, BMI, hernia width, or operative time lasting longer than 4 h. Median LOS was 8 days for patients with POI compared to five for those without ( p 
ISSN:1265-4906
1248-9204
1248-9204
DOI:10.1007/s10029-022-02687-7