Development of natamycin-loaded zein-casein composite nanoparticles by a pH-driven method and application to postharvest fungal control on peach against Monilinia fructicola

•Improve natamycin dispersibility by encapsulation for postharvest treatment.•A novel pH mixing-induced nanoprecipitation approach was developed.•Nata-Z/C NPs mainly interact via hydrophobic stacking and hydrogen bonds.•NPs improve the control of peach brown rot caused by Monilinia fructicola. This...

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Published in:Food chemistry 2023-03, Vol.404, p.134659-134659, Article 134659
Main Authors: Xu, Xuejiao, Peng, Xinlin, Huan, Chen, Chen, Jie, Meng, Yuecheng, Fang, Sheng
Format: Article
Language:English
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Monilinia fructicola
Nanoparticles
Natamycin
Postharvest peach brown rot
Zein
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cited_by cdi_FETCH-LOGICAL-c345t-76141ae9e55420f284c30152a2d5141761ed69c344257b716e019b98bc375cc13
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container_start_page 134659
container_title Food chemistry
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creator Xu, Xuejiao
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Chen, Jie
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description •Improve natamycin dispersibility by encapsulation for postharvest treatment.•A novel pH mixing-induced nanoprecipitation approach was developed.•Nata-Z/C NPs mainly interact via hydrophobic stacking and hydrogen bonds.•NPs improve the control of peach brown rot caused by Monilinia fructicola. This work fabricated natamycin-loaded zein-casein nanoparticles (N-Z/C NPs) by a pH-driven approach and applied to control postharvest peach brown rot caused by Monilinia fructicola. When casein and phosphoric acid were used as a stabilizer and neutralizing acid, respectively, NPs with mean particle sizes 
doi_str_mv 10.1016/j.foodchem.2022.134659
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This work fabricated natamycin-loaded zein-casein nanoparticles (N-Z/C NPs) by a pH-driven approach and applied to control postharvest peach brown rot caused by Monilinia fructicola. When casein and phosphoric acid were used as a stabilizer and neutralizing acid, respectively, NPs with mean particle sizes &lt; 100 nm and zeta-potentials &lt; −30 mV could be obtained. The NPs could increase the aqueous dispersibility of natamycin and showed high stability against environmental changes, which could be attributed to both hydrophobic stacking and hydrogen bonds between natamycin and zein. Besides, the effects of N-Z/C NPs on the storage of peach were assessed in vitro and in vivo. Nanoencapsulation did not affect the antifungal activities of natamycin. The NPs with 20 and 80 µg/mL of natamycin could basically inhibit the spore germination and mycelial growth of M. fructicola, respectively. 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subjects Monilinia fructicola
Nanoparticles
Natamycin
Postharvest peach brown rot
Zein
title Development of natamycin-loaded zein-casein composite nanoparticles by a pH-driven method and application to postharvest fungal control on peach against Monilinia fructicola
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