Regional oxygen saturation measured by two different oximetry monitors in infants and children undergoing living donor liver transplantation with bilirubin measurements: A prospective observational study

Background Tissue oximetry devices use wavelengths in the 680–870 nm range to separate between oxygenated/deoxygenated hemoglobin. Conjugated bilirubin has an absorption peak at 730 nm. Aims We hypothesized that ForeSight Elite using 5 wavelengths reduces interference from bilirubin and shows higher...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric anesthesia 2023-03, Vol.33 (3), p.201-210
Main Authors: Magasich‐Airola, Natalia Patricia, Momeni, Mona, Sanchez Torres, Cristel, De Magnée, Catherine, Tambucci, Roberto, Reding, Raymond, Pirotte, Thierry
Format: Article
Language:English
Subjects:
bilirubin
Bilirubin - analysis
Carbon Dioxide - analysis
Child
Child, Preschool
Hemoglobin
Hemoglobins - analysis
Humans
Hyperbilirubinemia
Infant
Liver Transplantation
Liver transplants
Living Donors
near‐infrared spectroscopy
Observational studies
Oximetry - methods
Oxygen - analysis
Oxygen Saturation
regional tissue oxygen saturation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Tissue oximetry devices use wavelengths in the 680–870 nm range to separate between oxygenated/deoxygenated hemoglobin. Conjugated bilirubin has an absorption peak at 730 nm. Aims We hypothesized that ForeSight Elite using 5 wavelengths reduces interference from bilirubin and shows higher regional tissue oxygen saturation (rSO2) than INVOS 5100C incorporating 2 wavelengths. Methods Infants and children undergoing living donor liver transplantation were included between March 2019 and September 2020. Cerebral and somatic rSO2 were measured, and real‐time simultaneous data were collected. Additionally, measurements were collected at (1) baseline, (2) beginning of dissection phase, (3) beginning of anhepatic phase, (4) reperfusion phase, and (5) skin closure. Bilirubin level was available at baseline and at reperfusion. Hyperbilirubinemia was defined as bilirubin level ≥1.0 mg/dl. Results Thirty‐three patients with median age of 27 months and median weight of 12 kg were included. Baseline bilirubin levels were higher compared to values at reperfusion (p = .021). A linear mixed effects model considering bilirubin as fixed and patient as random effect showed that there was a statistically significant difference in cerebral rSO2 readings in function of time (p = .031), device (p 
ISSN:1155-5645
1460-9592
DOI:10.1111/pan.14597