Significance of Baseline Ischemic Core Volume on Stroke Outcome After Endovascular Therapy in Patients Age ≥75 Years: A Pooled Analysis of Individual Patient Data From 7 Trials

Age and infarct volume are strong predictors of outcome in patients with ischemic stroke who underwent endovascular therapy (EVT). We aimed to investigate the impact of ischemic core volume (ICV) on stroke outcome after EVT in elderly. Using the HERMES (Highly Effective Reperfusion Using Multiple En...

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Bibliographic Details
Published in:Stroke (1970) 2022-12, Vol.53 (12), p.3564-3571
Main Authors: Tanaka, Koji, Goyal, Mayank, Menon, Bijoy K., Campbell, Bruce C.V., Mitchell, Peter J., Jovin, Tudor G., Dávalos, Antoni, Jansen, Olav, Muir, Keith W., White, Phil M., Bracard, Serge, Achit, Hamza, Dippel, Diederik W.J., Majoie, Charles B.L.M., Hill, Michael D., Brown, Scott, Demchuk, Andrew M.
Format: Article
Language:English
Subjects:
Aged
Brain Ischemia - diagnostic imaging
Brain Ischemia - surgery
Endovascular Procedures - methods
Humans
Randomized Controlled Trials as Topic
Reperfusion
Stroke - diagnostic imaging
Stroke - surgery
Thrombectomy - methods
Treatment Outcome
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Summary:Age and infarct volume are strong predictors of outcome in patients with ischemic stroke who underwent endovascular therapy (EVT). We aimed to investigate the impact of ischemic core volume (ICV) on stroke outcome after EVT in elderly. Using the HERMES (Highly Effective Reperfusion Using Multiple Endovascular Devices) collaboration, a patient-level meta-analysis of 7 randomized trials in which patients were enrolled from December 2010 to April 2015) dataset, we categorized patients into those aged
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.122.039774