Chronic vulvar fissure: approach with cross-linked hyaluronic acid

Introduction and hypothesis This report aims to prospectively describe the effectiveness and safety of injected cross-linked hyaluronic acid (HA) for the treatment of chronic vulvar fissures. Methods A descriptive prospective case series design including 15 patients affected by chronic vulvar fissur...

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Bibliographic Details
Published in:International Urogynecology Journal 2023-07, Vol.34 (7), p.1495-1499
Main Authors: González-Isaza, Pablo, Sánchez-Prieto, Manuel, Sánchez-Borrego, Rafael
Format: Article
Language:English
Subjects:
Atrophy
Dermatitis
Gynecology
Hyaluronic acid
Medicine
Medicine & Public Health
Obstetrics
Original Article
Patients
Questionnaires
Skin
Urology
Vagina
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Summary:Introduction and hypothesis This report aims to prospectively describe the effectiveness and safety of injected cross-linked hyaluronic acid (HA) for the treatment of chronic vulvar fissures. Methods A descriptive prospective case series design including 15 patients affected by chronic vulvar fissures who were treated with cross-linked HA filler between December 2020 and July 2021. The validated 21-item Vulvovaginal Symptoms Questionnaire (VSQ) was used to evaluate the results from baseline up to 9 months after the HA infiltration. Results A total of 15 patients suffering from chronic vulvar fissures were treated with an injection of 19 mg/mL HA filler. We found a significant improvement in VSQ scores at the end of the treatment compared to baseline. Patients reported excellent tolerance of the procedure, and no complications were recorded. Conclusions Cross-linked HA infiltration of the vulvar vestibule and posterior vaginal wall appeared to be a promising approach for chronic vulvar fissures.
ISSN:0937-3462
1433-3023
DOI:10.1007/s00192-022-05401-4