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Bronchopulmonary dysplasia is not related to neurofilament light for neuroaxonal damage in preterm infants

Background Neurofilament light (NfL) has been identified as a biomarker for neuroaxonal damage in preterm infants, but its relation with bronchopulmonary dysplasia (BPD) has not been established. We hypothesized that BPD is associated with increased NfL levels at an early stage, indicative of early...

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Published in:Pediatric research 2023-06, Vol.93 (7), p.2014-2018
Main Authors: Romijn, Michelle, Baas, Emma M., Lissenberg-Witte, Birgit I., Onland, Wes, Königs, Marsh, Oosterlaan, Jaap, Heijst, Hans, Rotteveel, Joost, van Kaam, Anton H., Teunissen, Charlotte E., Finken, Martijn J. J.
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Language:English
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Summary:Background Neurofilament light (NfL) has been identified as a biomarker for neuroaxonal damage in preterm infants, but its relation with bronchopulmonary dysplasia (BPD) has not been established. We hypothesized that BPD is associated with increased NfL levels at an early stage, indicative of early neuroaxonal damage. Methods We included preterm infants born
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-022-02365-5