Functional loss and worsening geriatric assessment parameters are more common in dementia with Lewy bodies than Alzheimer's disease

Background The main aim of this study was to compare older patients with Alzheimer's disease (AD) to those with dementia with Lewy bodies (DLB) according to their dependency in daily living activities and comprehensive geriatric assessment parameters. Method A total of 227 AD and 123 DLB patien...

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Bibliographic Details
Published in:Psychogeriatrics 2023-01, Vol.23 (1), p.77-85
Main Authors: Soysal, Pinar, Koc Okudur, Saadet, Uslu, Ferda, Smith, Lee
Format: Article
Language:English
Subjects:
Activities of Daily Living
Aged
Aged, 80 and over
Alzheimer Disease
Alzheimer's disease
Balance
Cardiovascular disease
Cognitive ability
Comorbidity
Coronary artery disease
Dementia
Dementia disorders
Female
Gait
Geriatric Assessment
Geriatrics
Hand Strength
Heart diseases
Humans
Lewy bodies
Lewy Body Disease
Male
Muscle strength
Neurodegenerative diseases
nutrition
sleep
Sleep and wakefulness
Sleep disorders
Statistical analysis
Urinary incontinence
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Summary:Background The main aim of this study was to compare older patients with Alzheimer's disease (AD) to those with dementia with Lewy bodies (DLB) according to their dependency in daily living activities and comprehensive geriatric assessment parameters. Method A total of 227 AD and 123 DLB patients underwent a geriatric assessment that included comorbidities, number of drugs used, falls, urinary incontinence, hand grip strength, Mini‐Nutritional Assessment (MNA), Tinetti Performance Oriented Mobility Assessment Scale, Insomnia Severity Index (ISI), and Epworth Sleepiness Scale. Basic and instrumental activities of daily living were assessed by the Barthel Index and the Lawton scale, respectively. Results The mean age of the participants was 83.4 years, and 73% were female. There were no statistically significant differences between AD and DLB patients in age, gender, cognitive function, or comorbidities except for coronary artery disease (P 
ISSN:1346-3500
1479-8301
DOI:10.1111/psyg.12905