Comparison of T2-weighted and diffusion-weighted imaging for the diagnosis of placenta accreta spectrum abnormality

• Published in: Acta radiologica (1987) 2023-04, Vol.64 (4), p.1694-1701
• Main Authors: Prakash, Adity, Kumar, Ishan, Verma, Ashish, Shukla, Ram C
• Format: Article
• Language: English
• Subjects: Diffusion Magnetic Resonance Imaging - methods; Female; Humans; Magnetic Resonance Imaging - methods; Placenta; Placenta Accreta - diagnostic imaging; Pregnancy; Retrospective Studies; Sensitivity and Specificity
• ISSN: 0284-1851; 1600-0455
• DOI: 10.1177/02841851221137274

Background Diffusion-weighted imaging (DWI) is feasible in prenatal imaging, and it exhibits better contrast between the placenta and the myometrium compared to T2-weighted (T2W) images. Purpose To compare magnetic resonance imaging (MRI) features of placenta accreta on T2W and DW imaging. Material and Methods In this retrospective study, 42 pregnant patients who underwent prenatal MRI were included. MRI was performed on a Siemens 1.5-T scanner. T2W and DWI sequences in the axial, sagittal, and/or coronal planes were compiled for review. Two radiologists independently interpreted T2W and DW images for placenta accreta. T2W and DWI scores were calculated based on the presence of features and graded as low, intermediate, and high risk. The association between imaging features and placental invasion on pathology was calculated using chi-square tests. Sensitivity, specificity, and positive and negative predictive values (NPV) were compared between T2W and DWI interpretations. Inter-reader agreement between the two radiologists for T2W and DWI scores was calculated using Cohen's kappa coefficient. Results Out of 42 pregnant patients, 10 were pathologically/surgically proven to have placenta accreta. There were no significant differences between T2W and DWI interpretations. Considering a cutoff >6 as positive, the T2W score had higher sensitivity (90% vs. 80%) and NPV (96.9% vs. 94.1%) than the DWI score. The specificity and positive predictive value were 100% for both scores. The inter-reader agreement of T2W score was higher (k = 0.943 vs. 0.882). Conclusion T2W and DWI are comparable in diagnosing placenta accreta spectrum. T2W sequences have higher sensitivity, NPV, and inter-reader agreement than DWI.