A novel retrograde technique for ankle osteochodral lesions: the sub-endo-chondral regenerative treatment (secret)

• Published in: Musculoskeletal surgery 2023-09, Vol.107 (3), p.337-343
• Main Authors: Faldini, C., Mazzotti, A., Artioli, E., Ruffilli, A., Barile, F., Zielli, S. O., Geraci, G.
• Format: Article
• Language: English
• Subjects: Ankle; Bone marrow; Cartilage; Cysts; Debridement; Hyaluronic acid; Medicine; Medicine & Public Health; Methods; Original Article; Orthopedics; Skin & tissue grafts; Surgical Orthopedics; Transplantation; X-rays
• ISSN: 2035-5106; 2035-5114
• DOI: 10.1007/s12306-022-00767-6

Purpose To describe a new surgical technique for osteochondral lesions of the ankle, using bone marrow concentrate on a scaffold and homologous bone graft positioned through a retrograde approach. Many surgical options for ankle osteochondral lesions have been described, and the ideal treatment is still debated. Bone marrow stimulating techniques are recommended for cystic lesions, with some concerns regarding the healing potential of the subchondral bone. In case of wide osteochondral defects, regenerative solutions are preferred but a massive chondral debridement is usually required. To overcome these problems, a novel technique is proposed. Methods The proposed technique was performed on patients affected by osteochondral lesions of the talus, either cysts with intact cartilage or wide osteochondral defects. A preoperative magnetic resonance imaging was obtained to localize the lesion. A 6-mm tarsal tunnel was retrogradely created toward the lesion, to allow a complete sub-endo-chondral debridement preserving the healthy cartilage. A hyaluronan scaffold soaked with a previously prepared bone marrow concentrate was retrogradely positioned under the cartilage surface and the tunnel was filled with homologous bone graft. Preoperative clinical scores and postoperative x-rays were registered. Results Four patients were treated using this technique. No intraoperative and postoperative complications occurred. Good bone remodeling was observed at 12-week postoperative x-rays. Conclusions This technique combines the mini-invasiveness of retrograde drilling with the regenerative properties of biological scaffold soaked with bone marrow concentrate. Despite further research being needed, it seems a new viable solution to treat both subchondral cysts and large osteochondral defects of the ankle, whose management is still controversial.