Three New Lanostanoids with Anti‐HCV Effects from Abies nukiangensis

Three new lanostane derivatives (1–3) and twelve known triterpenoids (4–15) were isolated from the twigs and leaves of Abies nukiangensis. The structures of the new compounds were elucidated mainly by detailed analysis of their NMR and HR‐ESI‐MS spectroscopic data. Evaluation of the anti‐HCV effects...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry & biodiversity 2022-12, Vol.19 (12), p.e202200941-n/a
Main Authors: Li, Yong‐Li, Xu, Zhuo‐Ni, Li, Jie, Liang, Shuang, Xue, Min‐Jie, Wu, Jian‐Jun, Yang, Xian‐Wen
Format: Article
Language:English
Subjects:
Abies
Abies - chemistry
Abies nukiangensis
hepatitis C virus (HCV)
Lanostanoids
Lanosterol
Magnetic Resonance Spectroscopy
Molecular Structure
NMR
Nuclear magnetic resonance
Pinaceae
Triterpenes - chemistry
Triterpenes - pharmacology
Triterpenoids
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Three new lanostane derivatives (1–3) and twelve known triterpenoids (4–15) were isolated from the twigs and leaves of Abies nukiangensis. The structures of the new compounds were elucidated mainly by detailed analysis of their NMR and HR‐ESI‐MS spectroscopic data. Evaluation of the anti‐HCV effects of all isolates showed that 3 exhibited moderate effect with the EC50 value of 11.09 μM.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202200941