Alcohol and health – Authors' reply

In our analysis,1 we estimated the theoretical minimum risk exposure level (TMREL) and the non-drinker equivalence of alcohol use, using a new approach to weight relative risk (RR) curves by estimated disability-adjusted life-years (DALYs) in every region, age, sex, and year. Manthey, Shield, and Re...

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Bibliographic Details
Published in:The Lancet (British edition) 2022-11, Vol.400 (10365), p.1766-1766
Main Authors: Bryazka, Dana, Griswold, Max G, Reitsma, Marissa B, Gakidou, Emmanuela
Format: Article
Language:English
Subjects:
Age
Alcohol use
Cardiovascular diseases
Cohort analysis
Estimates
Health risk assessment
Health risks
Citations: Items that this one cites
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Summary:In our analysis,1 we estimated the theoretical minimum risk exposure level (TMREL) and the non-drinker equivalence of alcohol use, using a new approach to weight relative risk (RR) curves by estimated disability-adjusted life-years (DALYs) in every region, age, sex, and year. Manthey, Shield, and Rehm suggest our RR results do not incorporate known age-effects and regional effects modifying the relationship between alcohol use and disease outcomes, and C Mary Schooling and Gabriel M Leung note that our RR estimates could reflect survival bias in participant recruitment. Many of the available cohort studies recruit older participants as part of trials on cardiovascular disease or cancers.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(22)02121-3