Regulation of male sex hormones strongly heightens copulation behavior indices in rat’s model administered Cocos nucifera husks extract

• Published in: African health sciences 2022-06, Vol.22 (2), p.410-419
• Main Authors: Bolaji Odigie, Efosa, Emosho Atoigwe, Blessing, Francis, Blessing, Kehinde Lawal, Monsurat, Ogie Erameh, Theophilus, Nwaobi, Anthony, Precious Arugba, Ewamazino
• Format: Article
• Language: English
• ISSN: 1680-6905; 1680-6905; 1729-0503
• DOI: 10.4314/ahs.v22i2.47

Background: Cocos nucifera (Coconut, Arecaceae family) is consumed as dietary fruit but little is known of it as sex enhancer. Objective: To investigate male sex hormones and copulation behavior indices in male Wistar rats administered husks extract. Materials and Methods: Rats were grouped into control A, and treatment B to E (n=4); and administered husks extract at varying doses: 125mg/kg, 250mg/kg, 375mg/kg and 500mg/kg for 48days by oral intubation. Copulation behavior was assessed by introducing female rats to males (1:1) in a rectangular Plexiglas chamber and monitored by veterinary Anatomists. Blood samples for male sex hormones were collected and assayed by ELISA method. Results: Copulation behavior (500mg/kg treatment): mounting (9.66±0.79 to 29.08±2.16), ejaculation (7.66±0.38 to 16.93±0.76), intromission (22.01±1.67 to 38.11±3.35) frequencies, and ejaculation latency (7.92±0.43 to 12.28±0.41) increased remarkably (Group E). Correspondingly, mounting (133.31±1.18 to 93.39±0.43) and, intromission (88.13±3.12 to 74.55±1.19) latencies; post-ejaculation (3.16±0.14 to 2.18±0.34), inter-intromission (19.48±0.26 to 14.32±1.65) intervals reduced significantly (P≤0.05). Testosterone levels (Group E) increased: 3.82±0.6ng/dL to 5.14±0.3ng/dL while, LH and FSH values reduced: 2.92±0.6IU/L to 2.13±0.3IU/L and 2.28±0.7IU/L to 1.58±0.3IU/L significantly (p ≤ 0.05) while changes were dose-related. Conclusion: C. nucifera husks extract improves sexuality indices by regulating male sex hormones in male Wistar rats. Keywords: Cocos nucifera; coconut husk; Coconut fibre; copulation behaviour; male sex hormones; mating profile; hormonal indices; libido; natural sex enhancer; medicinal values.