Sexually acquired severe acute hepatitis C infection in men who have sex with men

Acute infection with hepatitis C virus (HCV) is a cause of severe acute hepatitis. Sexual transmission of acute HCV is uncommon, but risk is accentuated in individuals who engage in receptive anal sex. In acute HCV infection, testing by polymerase chain reaction (PCR) returns positive results, but r...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2022-11, Vol.194 (45), p.E1537-E1540
Main Authors: Wei, Sunny, Bogoch, Isaac I, Dhalla, Irfan A, Wong, David K H
Format: Article
Language:English
Subjects:
Antibodies
Antiviral agents
Care and treatment
Cocaine
Development and progression
Dosage and administration
Emergency medical care
Enzymes
Gays & lesbians
Health aspects
Hepatitis
Hepatitis C
Hepatitis C - epidemiology
HIV
Homosexuality, Male
Hospitals
Human immunodeficiency virus
Humans
Infections
Laboratories
Liver
Male
Men
Mens health
MSM (Men who have sex with men)
Patients
Prevention
Public health
Serology
Sexual and Gender Minorities
Sexual Behavior
Sexually transmitted diseases
Social aspects
Social networks
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Summary:Acute infection with hepatitis C virus (HCV) is a cause of severe acute hepatitis. Sexual transmission of acute HCV is uncommon, but risk is accentuated in individuals who engage in receptive anal sex. In acute HCV infection, testing by polymerase chain reaction (PCR) returns positive results, but results from tests of anti-HCV antibodies are typically negative for several weeks after exposure. Some public health laboratories allow for HCV PCR testing only if the anti-HCV antibody test result is positive, which can make diagnosing acute HCV infection challenging.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.220757