Immunoprotective role of aloin and disease resistance in Labeo rohita, infected with bacterial fish pathogen, Aeromonas hydrophila

• Published in: Environmental science and pollution research international 2023-03, Vol.30 (11), p.30062-30072
• Main Authors: Srivastava, Ayan, Kumari, Usha, Mittal, Swati, Mittal, Ajay Kumar
• Format: Article
• Language: English
• Subjects: Aeromonas hydrophila; Animals; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Cyprinidae; Disease Resistance; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Fish Diseases - microbiology; Gram-Negative Bacterial Infections - veterinary; Research Article; Waste Water Technology; Water Management; Water Pollution Control
• ISSN: 1614-7499; 1614-7499
• DOI: 10.1007/s11356-022-24253-5

The effect of aloin on mucosal immune response and disease resistance was elucidated in Labeo rohita infected with the bacterial fish pathogen, Aeromonas hydrophila . Fishes were divided into four groups: (i) control, (ii) vehicle control, (iii) bacteria infected and (iv) bacteria infected and aloin treated. Fish were intraperitoneally injected with A. hydrophila suspension at the dose of 2 × 10 6  CFU/fish at 0 day (d). Following bacterial injection at 0 d, fish were treated with aloin at a dose of 1 mg/kg body weight intraperitoneally at an interval of 24 h for 4 consecutive days. Mucus collected from fish of each group was analyzed at 2 d, 4 d, 6 d, 8 d and 10 d. In bacteria-infected fish, a significant decrease ( P