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Decline of RSV-specific antibodies during the COVID-19 pandemic
Lifting these measures resulted in out-of-season RSV activity, sometimes exceeding the incidence of hospitalisations observed in regular seasons.1–3 Declining immunity due to reduced exposure to the virus may contribute to this altered epidemiology.1,4,5 Bardsley and colleagues1 showed that the comb...
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Published in: | The Lancet infectious diseases 2023-01, Vol.23 (1), p.23-25 |
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creator | den Hartog, Gerco van Kasteren, Puck B Schepp, Rutger M Teirlinck, Anne C van der Klis, Fiona R M van Binnendijk, Robert S |
description | Lifting these measures resulted in out-of-season RSV activity, sometimes exceeding the incidence of hospitalisations observed in regular seasons.1–3 Declining immunity due to reduced exposure to the virus may contribute to this altered epidemiology.1,4,5 Bardsley and colleagues1 showed that the combination of laboratory, clinical, and syndromic data capture the impact of RSV activity, yet did not provide insight into the proposed decline in immunity. The repeated-measures general linear model (SPSS version 28; IBM, Armonk, NY, USA) was used to compare antibody concentrations between sampling timepoints of the same subjects and between age groups. p values, adjusted to Bonferroni and Benjamini-Hochberg procedures, are reported for timepoints and age-group differences respectively. [...]monitoring changes in antibody concentrations could identify populations susceptible to RSV infection. |
doi_str_mv | 10.1016/S1473-3099(22)00763-0 |
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subjects | Age groups Antibodies Antibodies, Neutralizing Coronaviruses COVID-19 Epidemiology Humans Immunity Infectious diseases Laboratories Pandemics Respiratory syncytial virus Respiratory Syncytial Virus Infections - epidemiology Respiratory Syncytial Virus, Human Seasons |
title | Decline of RSV-specific antibodies during the COVID-19 pandemic |
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