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Validation of the anterior skull base questionnaire 35 in endoscopic pituitary adenoma surgery

Patient quality of life (QOL) is an important metric of surgical success. To guide therapeutic advances in pituitary adenoma surgery, a validated, comprehensive instrument to quantify QOL is required. We aim to evaluate the validity of the 35 item anterior skull base questionnaire (ASBQ-35) in patie...

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Published in:Neurosurgical review 2022-12, Vol.46 (1), p.7-7, Article 7
Main Authors: Castle-Kirszbaum, Mendel, Wang, Yi Yuen, King, James, Kam, Jeremy, Shi, Margaret D. Y., Goldschlager, Tony
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Wang, Yi Yuen
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Goldschlager, Tony
description Patient quality of life (QOL) is an important metric of surgical success. To guide therapeutic advances in pituitary adenoma surgery, a validated, comprehensive instrument to quantify QOL is required. We aim to evaluate the validity of the 35 item anterior skull base questionnaire (ASBQ-35) in patients undergoing pituitary adenoma surgery. A total of 168 patients undergoing endoscopic resection of pituitary adenomas underwent longitudinal QOL assessment using the ASBQ-35 and the 22-item Sinonasal Outcomes Test (SNOT-22) over the first postoperative year. Validity of the ASBQ-35 was assessed by internal consistency, test–retest reliability, responsiveness to clinical change, and concurrent validity with the SNOT-22. Internal consistency of the ASBQ-35 was excellent, with a Cronbach’s alpha > 0.95 across all timepoints. Test–retest reliability between 3 and 6 months (ICC = 0.82, p  
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source Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List
subjects Humans
Medicine
Medicine & Public Health
Neurosurgery
Pituitary Neoplasms - surgery
Quality of Life
Reproducibility of Results
Skull Base
title Validation of the anterior skull base questionnaire 35 in endoscopic pituitary adenoma surgery
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