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Differences in medication adherence by sex and organ type among adolescent and young adult solid organ transplant recipients

Background Identification of differences in medication adherence by sex or organ type may help in planning interventions to optimize outcomes. We compared immunosuppressive medication adherence between males and females, and between kidney, liver and heart transplant recipients. Methods This multice...

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Published in:Pediatric transplantation 2023-03, Vol.27 (2), p.e14446-n/a
Main Authors: Vaisbourd, Yulia, Dahhou, Mourad, Zhang, Xun, Sapir‐Pichhadze, Ruth, Cardinal, Heloise, Johnston, Olwyn, Blydt‐Hansen, Tom D., Tibbles, Lee Anne, Hamiwka, Lorraine, Urschel, Simon, Birk, Patricia, Bissonnette, Janice, Matsuda‐Abedini, Mina, BScPhm, Jennifer Harrison, Schiff, Jeffrey, Phan, Veronique, De Geest, Sabina, Allen, Upton, Avitzur, Yaron, Mital, Seema, Foster, Bethany J.
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Language:English
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Summary:Background Identification of differences in medication adherence by sex or organ type may help in planning interventions to optimize outcomes. We compared immunosuppressive medication adherence between males and females, and between kidney, liver and heart transplant recipients. Methods This multicenter study of prevalent kidney, liver and heart transplant recipients 14–25 years assessed adherence 3 times (0, 3, 6 months post‐enrollment) with the BAASIS self‐report tool. At each visit, participants were classified as adherent if they missed no doses in the prior 4 weeks and non‐adherent otherwise. Adherence was also assessed using the coefficient of variation (CV) of tacrolimus trough levels; CV 
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.14446