Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis

Purpose To evaluate the effect of total parathyroidectomy (tPTx) on malnutrition and inflammation in patients on maintenance dialysis (MHD) having secondary hyperparathyroidism (SHPT). Methods Twenty-five patients on MHD having SHPT who were being treated with tPTx were selected, and changes in thei...

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Published in:International urology and nephrology 2023-05, Vol.55 (5), p.1301-1309
Main Authors: Zhou, Xiaochun, Kong, Yuke, Ma, Zhigang, Liu, Tianxi, Wan, Tingxin, Zhang, Wenjun, Zhao, Pengming, Wang, Ya, Ma, Li, Wang, Gouqin, Wang, Xiaoling, Liang, Yaojun, Du, Xuan, Ning, Yaxian, Deng, Rongrong, Tang, Ya, Hu, Weiwei, Wang, Jianqin
Format: Article
Language:English
Subjects:
Albumin
Body mass
C-Reactive Protein
Calcium
Dialysis
Hematocrit
Hemodialysis
Hemoglobin
Hemoglobins
Humans
Hyperparathyroidism
Hyperparathyroidism, Secondary - complications
Hyperparathyroidism, Secondary - surgery
Inflammation
Inflammation - complications
Interleukin 6
Kidney Failure, Chronic - surgery
Kidney Failure, Chronic - therapy
Malnutrition
Malnutrition - complications
Malnutrition - etiology
Medicine
Medicine & Public Health
Nephrology
Nephrology - Original Paper
Parathyroid Hormone
Parathyroidectomy
Quality of Life
Renal Dialysis
Serum Albumin
Tumor Necrosis Factor-alpha
Tumor necrosis factor-TNF
Tumor necrosis factor-α
Urology
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Summary:Purpose To evaluate the effect of total parathyroidectomy (tPTx) on malnutrition and inflammation in patients on maintenance dialysis (MHD) having secondary hyperparathyroidism (SHPT). Methods Twenty-five patients on MHD having SHPT who were being treated with tPTx were selected, and changes in their general condition (dry body mass), parathyroid hormone (PTH) and calcium levels, nutrition state (hemoglobin, hematocrit, serum albumin, and total iron binding capacity), and inflammatory status [serum C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and the malnutrition–inflammation score (MIS)] were observed at 12, 24, and 36 months postoperatively. Results Compared with the preoperative period, the dry body mass increased at 12, 24, and 36 months postoperatively ( P  
ISSN:1573-2584
0301-1623
1573-2584
DOI:10.1007/s11255-022-03436-6