Sexual and Reproductive Health Outcomes in Females With Cloacal Malformations and Other Anorectal Malformations

• Published in: Journal of pediatric & adolescent gynecology 2023-04, Vol.36 (2), p.148-154
• Main Authors: Ahmad, Hira, Knaus, Maria E., Gasior, Alessandra C., Jimenez, Alberta Negri, Spieth, Paige T., Srinivas, Shruthi, Stanek, Joseph R., Levitt, Marc A., Wood, Richard J., Hewitt, Geri D., McCracken, Kate A.
• Format: Article
• Language: English
• Subjects: Animals; Anorectal malformation; Anorectal Malformations; Child; Cloaca; Cloaca - abnormalities; Cross-Sectional Studies; Dyspareunia; Female; Humans; Infant, Newborn; Pregnancy; Quality of Life; Reproductive Health; Sexual function; Vagina - abnormalities; Vaginal graft
• ISSN: 1083-3188; 1873-4332
• DOI: 10.1016/j.jpag.2022.10.008

To improve our understanding of reproductive health and sexual function in women with cloacal malformations and other anorectal malformations (ARMs) An observational cross-sectional survey was administered to individuals assigned female at birth aged 12 to 55 with ARMs and cloacal malformations cared for at our institution. Data included age of thelarche/menarche and questions on body image, gynecologic anatomy, sexual function, and pregnancy. Twenty-one patients responded in the ARM group and 30 in the cloacal malformation group. There were no differences in median age of thelarche/menarche in patients with ARMs (11/12.5 years) compared with patients with cloacal malformation (11/12 years). Patients with ARMs were more likely to have native vaginal tissue than those with cloacal malformations (n = 18, 82% vs n = 12, 40%; P = .03). There were no differences between groups regarding concerns about dyspareunia and functionality of their vagina (P > .05). Forty-two percent of patients with cloacal malformations and 30% of patients with ARMs reported having been sexually active. Two patients with cloacal malformations and 2 with ARMs reported having been pregnant. Patients with cloacal malformations reported a lower quality of life score (80.4) compared with those with ARMs (87.0) (difference > 4.5). Patients with a cloacal malformation were less likely to have native vaginal tissue and reported a lower quality of life than those with ARMs. Despite this, patients with a cloacal malformation had similar reproductive health and sexual function compared with patients with ARMs. Our results reinforce the need for comprehensive sexual and reproductive health care for all women with ARMs.