Outcomes of concomitant aortic valve procedures and left ventricular assist device implantation: A systematic review and meta‐analysis

Background Left ventricular assist device (LVAD) implantation is frequently employed in patients with end‐stage heart failure. The outcomes of addressing the repair of all substantial aortic valvular disease at the time of LVAD implantation remain unclear. We sought to assess the clinical outcomes i...

Full description

Saved in:
Bibliographic Details
Published in:Artificial organs 2023-03, Vol.47 (3), p.470-480
Main Authors: Iqbal, Kinza, Arif, Taha Bin, Rathore, Sawai Singh, Ahmed, Jawad, Kumar, Pankaj, Shahid, Izza, Iqbal, Ayman, Shariff, Mariam, Kumar, Ashish
Format: Article
Language:English
Subjects:
Aorta
Aortic Valve
aortic valve repair
aortic valve replacement
Congestive heart failure
Heart Failure
Heart valves
Heart-Assist Devices
Humans
Implantation
left ventricular assist device
Meta-analysis
Mortality
outcomes
Patients
Retrospective Studies
Rheumatic heart disease
Stroke
Survival
Thoracic Surgical Procedures
Treatment Outcome
Ventricle
Ventricular assist devices
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Left ventricular assist device (LVAD) implantation is frequently employed in patients with end‐stage heart failure. The outcomes of addressing the repair of all substantial aortic valvular disease at the time of LVAD implantation remain unclear. We sought to assess the clinical outcomes in patients undergoing LVAD implantation concomitant with aortic valve procedures (AVPs) compared with isolated LVAD implantation. Methods A literature search was performed using PubMed, Embase, and Cochrane library from inception till June 2022. Primary outcomes included short‐term mortality and long‐term survival. Random effects models were used to compute mean differences and odds ratios with 95% confidence intervals (CIs). Results A total of 14 observational studies (N = 52 693) met our inclusion criteria. Concomitant LVAD implantation and AVPs were associated with higher short‐term mortality (OR = 1.61 [95% CI, 1.06–2.42]; p = 0.02) and mean CPBt (MD = 43.25 [95% CI, 22.95–63.56]; p 
ISSN:0160-564X
1525-1594
DOI:10.1111/aor.14482