Post-radiotherapy cribriform-morular thyroid carcinoma

BACKGROUNDAccording to the new 2022 World Health Organization classification of endocrine tumors, thyroid malignancy, formerly known as the cribriform-morular variant of papillary thyroid carcinoma, is now categorized as differentiated thyroid malignancy; it is, at present, called cribriform-morular...

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Bibliographic Details
Published in:Journal of clinical laboratory analysis 2023, Vol.37 (1), p.e24819-e24819
Main Authors: Or Koca, Arzu, Güler Şimşek, Gülçin
Format: Report
Language:English
Online Access:Get full text
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Summary:BACKGROUNDAccording to the new 2022 World Health Organization classification of endocrine tumors, thyroid malignancy, formerly known as the cribriform-morular variant of papillary thyroid carcinoma, is now categorized as differentiated thyroid malignancy; it is, at present, called cribriform-morular thyroid carcinoma and classified as a tumor of unknown histogenesis. CASE REPORTIn this case report, we report on a 15-year-old patient who underwent external radiotherapy to the neck for Hodgkin's disease and developed cribriform-morular thyroid carcinoma 5 years after radiotherapy. CONCLUSIONSWe believe that cribriform-morular thyroid carcinoma with diffuse nuclear beta-catenin expression has exciting and unresolved uncertainties that may affect disease prognosis and follow-up for cytopathologists and endocrinologists.
ISSN:1098-2825
DOI:10.1002/jcla.24819