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Establishment of measles virus receptor‐expressing Vero cells lacking functional poliovirus receptors
Global efforts are underway to eliminate measles and rubella, and active viral surveillance is the key to achieving this goal. In addition, the World Health Organization announced guidelines for handling materials potentially infectious for poliovirus (PV) to minimize the risk of PV reintroduction a...
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Published in: | Microbiology and immunology 2023-03, Vol.67 (3), p.166-170 |
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container_end_page | 170 |
container_issue | 3 |
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container_title | Microbiology and immunology |
container_volume | 67 |
creator | Someya, Kenji Okemoto‐Nakamura, Yuko Kurata, Takako Kanbayashi, Daiki Saito, Noriko Itamochi, Masae Otsuki, Noriyuki Hanada, Kentaro Takeda, Makoto |
description | Global efforts are underway to eliminate measles and rubella, and active viral surveillance is the key to achieving this goal. In addition, the World Health Organization announced guidelines for handling materials potentially infectious for poliovirus (PV) to minimize the risk of PV reintroduction and to achieve PV eradication. To support global efforts, we established new PV‐non‐susceptible cell lines that are useful for the isolation of measles virus (MeV) and rubella virus (RuV) (Vero ΔPVR1/2 hSLAM+). In the cell lines, MeV and RuV replicated efficiently, with no concern regarding PV replication. |
doi_str_mv | 10.1111/1348-0421.13047 |
format | article |
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source | Wiley; Alma/SFX Local Collection |
subjects | Animals Cell lines Chlorocebus aethiops Humans Measles - epidemiology Measles virus Poliovirus receptor Receptors, Virus - genetics Rubella Rubella virus SLAM Vero Cells Viruses |
title | Establishment of measles virus receptor‐expressing Vero cells lacking functional poliovirus receptors |
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