Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings

Selenium (Se) is an essential element and antioxidant that catalyzes the destruction of hydrogen peroxide formed during cellular oxidative metabolism. Doses of Se as selenomethionine (SeMe) by oral route are 0.1–0.3 mgSe/kg DM, while the dose by parenteral route with sodium selenite (Na 2 SeO 3 ) is...

Full description

Saved in:
Bibliographic Details
Published in:Biological trace element research 2023-09, Vol.201 (9), p.4374-4388
Main Authors: Ortiz-Morales, Oscar, Ramírez-Bribiesca, J. Efrén, Hernández-Bautista, Jorge, Hernández-Sánchez, David, Bárcena-Gama, José Ricardo, Hernández-Trujillo, Elein, Díaz-Sánchez, Victor M., Garrido-Fariña, German, López-Ojeda, José C., Hernández-Rodriguez, Martha
Format: Article
Language:English
Subjects:
aerobiosis
Bioavailability
Biochemistry
Biomedical and Life Sciences
Biotechnology
Dosage
Dystrophy
Feed conversion
Food conversion
goat milk
Goats
growth performance
Histopathology
Hydrogen peroxide
Kidneys
Lesions
Life Sciences
Liver
Meat
Metabolism
Milk
Muscular dystrophy
Neonates
Nutrition
Oncology
Oral administration
Oxidative metabolism
Selenium
Selenomethionine
Sodium
Sodium selenite
Tissue
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43
cites cdi_FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43
container_end_page 4388
container_issue 9
container_start_page 4374
container_title Biological trace element research
container_volume 201
creator Ortiz-Morales, Oscar
Ramírez-Bribiesca, J. Efrén
Hernández-Bautista, Jorge
Hernández-Sánchez, David
Bárcena-Gama, José Ricardo
Hernández-Trujillo, Elein
Díaz-Sánchez, Victor M.
Garrido-Fariña, German
López-Ojeda, José C.
Hernández-Rodriguez, Martha
description Selenium (Se) is an essential element and antioxidant that catalyzes the destruction of hydrogen peroxide formed during cellular oxidative metabolism. Doses of Se as selenomethionine (SeMe) by oral route are 0.1–0.3 mgSe/kg DM, while the dose by parenteral route with sodium selenite (Na 2 SeO 3 ) is 0.1 mgSe/BW. The effects of supranutritional Se supplementation on normal kids have rarely been studied. The objective of the study was to evaluate both Se sources on growth performance, Se in tissues, histopathological findings, and meat characteristics. Forty-five kids of the Pastoreña breed with 25-day age were distributed (4.7 ± 1.13 kg) in three treatments: a) control group, C: consumption with goat milk (GM: containing 0.135 mgSe/g); b) NaSe: GM plus Na 2 SeO 3 injectable, 0.25 mgSe/kg BW; c) SeMe: GM plus oral dosage, 0.3 mgSe as SeMe daily. Fifteen animals per treatment were slaughtered at 7, 14, and 21 days. Feed conversion improved ( P  
doi_str_mv 10.1007/s12011-022-03528-5
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2758576501</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2838106734</sourcerecordid><originalsourceid>FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43</originalsourceid><addsrcrecordid>eNqFkstuEzEUhi0EomnhBVggS2xYZMD3mVmi0psIEKnZjxzPceJqxg62p1LfjMfDSQqVWMDKi_8737HsH6E3lHyghNQfE2WE0oowVhEuWVPJZ2hGpWwrUjPyHM0IVbwSbSNO0GlKd4TQmrX8JTrhStaCKjVDPy-sBZNxsPh22kXtpxxddsHrAX8OSW8A38IA3k0jdh5_g5Lkkl0FnfEX1yccPF7G0E8mu3vAS4g2xFF7A3O83D4kZ4LZwuhMGSqcdQOkvekr6Dx_ci_gHoZDsHIpTZDmWPseX7uUw07nbRjC5uC4dL53fpNeoRdWDwleP55naHV5sTq_rhbfr27OPy0qI0iTK6agN61QwlhjZaOhBqq0bmslhFgr03DVK6vJGlSjaiNhTZWR3CrWK2oFP0Pvj9pdDD_KtXI3umRgGLSHMKWOU8kZkbyh_0VZLRtZK0n26Lu_0LswxfLmhWqKi6ia73ezI2ViSCmC7XbRjTo-dJR0-wZ0xwZ0pQHdoQGdLENvH9XTeoT-z8jvLy8APwKpRH4D8Wn3P7S_ALQbvlU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2838106734</pqid></control><display><type>article</type><title>Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings</title><source>Springer Nature</source><creator>Ortiz-Morales, Oscar ; Ramírez-Bribiesca, J. Efrén ; Hernández-Bautista, Jorge ; Hernández-Sánchez, David ; Bárcena-Gama, José Ricardo ; Hernández-Trujillo, Elein ; Díaz-Sánchez, Victor M. ; Garrido-Fariña, German ; López-Ojeda, José C. ; Hernández-Rodriguez, Martha</creator><creatorcontrib>Ortiz-Morales, Oscar ; Ramírez-Bribiesca, J. Efrén ; Hernández-Bautista, Jorge ; Hernández-Sánchez, David ; Bárcena-Gama, José Ricardo ; Hernández-Trujillo, Elein ; Díaz-Sánchez, Victor M. ; Garrido-Fariña, German ; López-Ojeda, José C. ; Hernández-Rodriguez, Martha</creatorcontrib><description>Selenium (Se) is an essential element and antioxidant that catalyzes the destruction of hydrogen peroxide formed during cellular oxidative metabolism. Doses of Se as selenomethionine (SeMe) by oral route are 0.1–0.3 mgSe/kg DM, while the dose by parenteral route with sodium selenite (Na 2 SeO 3 ) is 0.1 mgSe/BW. The effects of supranutritional Se supplementation on normal kids have rarely been studied. The objective of the study was to evaluate both Se sources on growth performance, Se in tissues, histopathological findings, and meat characteristics. Forty-five kids of the Pastoreña breed with 25-day age were distributed (4.7 ± 1.13 kg) in three treatments: a) control group, C: consumption with goat milk (GM: containing 0.135 mgSe/g); b) NaSe: GM plus Na 2 SeO 3 injectable, 0.25 mgSe/kg BW; c) SeMe: GM plus oral dosage, 0.3 mgSe as SeMe daily. Fifteen animals per treatment were slaughtered at 7, 14, and 21 days. Feed conversion improved ( P  &lt; 0.05) with Se supplement ( P  &lt; 0.05) at 7 and 14 days. SeMe had higher protein and fat meat content ( P  &lt; 0.05). SeMe increased Se liver at 14 and 21 days. NaSe and SeMe had higher ( P  &lt; 0.05) levels of Se kidney. SeMe-21d showed 42% mononuclear and periportal cell infiltration lesions. In conclusion, Se administered through milk in goat kids was insufficient to prevent nutritional muscular dystrophy. The supranutritional dose of 0.25 mg/kg as NaSe was sufficient to maintain the Se level in tissues. SeMe increased Se liver and kidney efficiently. Both Se sources improved the bioavailability of the mineral in kids.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-022-03528-5</identifier><identifier>PMID: 36574166</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>aerobiosis ; Bioavailability ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Dosage ; Dystrophy ; Feed conversion ; Food conversion ; goat milk ; Goats ; growth performance ; Histopathology ; Hydrogen peroxide ; Kidneys ; Lesions ; Life Sciences ; Liver ; Meat ; Metabolism ; Milk ; Muscular dystrophy ; Neonates ; Nutrition ; Oncology ; Oral administration ; Oxidative metabolism ; Selenium ; Selenomethionine ; Sodium ; Sodium selenite ; Tissue</subject><ispartof>Biological trace element research, 2023-09, Vol.201 (9), p.4374-4388</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43</citedby><cites>FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43</cites><orcidid>0000-0003-2137-9315 ; 0000-0002-8306-1516 ; 0000-0001-7575-8180 ; 0000-0002-8761-3656 ; 0000-0001-7286-0382 ; 0000-0001-8637-5142 ; 0000-0002-0039-9424 ; 0000-0002-3281-5840 ; 0000-0002-2549-3353 ; 0000-0002-9295-8819</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36574166$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ortiz-Morales, Oscar</creatorcontrib><creatorcontrib>Ramírez-Bribiesca, J. Efrén</creatorcontrib><creatorcontrib>Hernández-Bautista, Jorge</creatorcontrib><creatorcontrib>Hernández-Sánchez, David</creatorcontrib><creatorcontrib>Bárcena-Gama, José Ricardo</creatorcontrib><creatorcontrib>Hernández-Trujillo, Elein</creatorcontrib><creatorcontrib>Díaz-Sánchez, Victor M.</creatorcontrib><creatorcontrib>Garrido-Fariña, German</creatorcontrib><creatorcontrib>López-Ojeda, José C.</creatorcontrib><creatorcontrib>Hernández-Rodriguez, Martha</creatorcontrib><title>Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>Selenium (Se) is an essential element and antioxidant that catalyzes the destruction of hydrogen peroxide formed during cellular oxidative metabolism. Doses of Se as selenomethionine (SeMe) by oral route are 0.1–0.3 mgSe/kg DM, while the dose by parenteral route with sodium selenite (Na 2 SeO 3 ) is 0.1 mgSe/BW. The effects of supranutritional Se supplementation on normal kids have rarely been studied. The objective of the study was to evaluate both Se sources on growth performance, Se in tissues, histopathological findings, and meat characteristics. Forty-five kids of the Pastoreña breed with 25-day age were distributed (4.7 ± 1.13 kg) in three treatments: a) control group, C: consumption with goat milk (GM: containing 0.135 mgSe/g); b) NaSe: GM plus Na 2 SeO 3 injectable, 0.25 mgSe/kg BW; c) SeMe: GM plus oral dosage, 0.3 mgSe as SeMe daily. Fifteen animals per treatment were slaughtered at 7, 14, and 21 days. Feed conversion improved ( P  &lt; 0.05) with Se supplement ( P  &lt; 0.05) at 7 and 14 days. SeMe had higher protein and fat meat content ( P  &lt; 0.05). SeMe increased Se liver at 14 and 21 days. NaSe and SeMe had higher ( P  &lt; 0.05) levels of Se kidney. SeMe-21d showed 42% mononuclear and periportal cell infiltration lesions. In conclusion, Se administered through milk in goat kids was insufficient to prevent nutritional muscular dystrophy. The supranutritional dose of 0.25 mg/kg as NaSe was sufficient to maintain the Se level in tissues. SeMe increased Se liver and kidney efficiently. Both Se sources improved the bioavailability of the mineral in kids.</description><subject>aerobiosis</subject><subject>Bioavailability</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Dosage</subject><subject>Dystrophy</subject><subject>Feed conversion</subject><subject>Food conversion</subject><subject>goat milk</subject><subject>Goats</subject><subject>growth performance</subject><subject>Histopathology</subject><subject>Hydrogen peroxide</subject><subject>Kidneys</subject><subject>Lesions</subject><subject>Life Sciences</subject><subject>Liver</subject><subject>Meat</subject><subject>Metabolism</subject><subject>Milk</subject><subject>Muscular dystrophy</subject><subject>Neonates</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Oral administration</subject><subject>Oxidative metabolism</subject><subject>Selenium</subject><subject>Selenomethionine</subject><subject>Sodium</subject><subject>Sodium selenite</subject><subject>Tissue</subject><issn>0163-4984</issn><issn>1559-0720</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFkstuEzEUhi0EomnhBVggS2xYZMD3mVmi0psIEKnZjxzPceJqxg62p1LfjMfDSQqVWMDKi_8737HsH6E3lHyghNQfE2WE0oowVhEuWVPJZ2hGpWwrUjPyHM0IVbwSbSNO0GlKd4TQmrX8JTrhStaCKjVDPy-sBZNxsPh22kXtpxxddsHrAX8OSW8A38IA3k0jdh5_g5Lkkl0FnfEX1yccPF7G0E8mu3vAS4g2xFF7A3O83D4kZ4LZwuhMGSqcdQOkvekr6Dx_ci_gHoZDsHIpTZDmWPseX7uUw07nbRjC5uC4dL53fpNeoRdWDwleP55naHV5sTq_rhbfr27OPy0qI0iTK6agN61QwlhjZaOhBqq0bmslhFgr03DVK6vJGlSjaiNhTZWR3CrWK2oFP0Pvj9pdDD_KtXI3umRgGLSHMKWOU8kZkbyh_0VZLRtZK0n26Lu_0LswxfLmhWqKi6ia73ezI2ViSCmC7XbRjTo-dJR0-wZ0xwZ0pQHdoQGdLENvH9XTeoT-z8jvLy8APwKpRH4D8Wn3P7S_ALQbvlU</recordid><startdate>20230901</startdate><enddate>20230901</enddate><creator>Ortiz-Morales, Oscar</creator><creator>Ramírez-Bribiesca, J. Efrén</creator><creator>Hernández-Bautista, Jorge</creator><creator>Hernández-Sánchez, David</creator><creator>Bárcena-Gama, José Ricardo</creator><creator>Hernández-Trujillo, Elein</creator><creator>Díaz-Sánchez, Victor M.</creator><creator>Garrido-Fariña, German</creator><creator>López-Ojeda, José C.</creator><creator>Hernández-Rodriguez, Martha</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7QP</scope><scope>7TN</scope><scope>7U7</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><orcidid>https://orcid.org/0000-0003-2137-9315</orcidid><orcidid>https://orcid.org/0000-0002-8306-1516</orcidid><orcidid>https://orcid.org/0000-0001-7575-8180</orcidid><orcidid>https://orcid.org/0000-0002-8761-3656</orcidid><orcidid>https://orcid.org/0000-0001-7286-0382</orcidid><orcidid>https://orcid.org/0000-0001-8637-5142</orcidid><orcidid>https://orcid.org/0000-0002-0039-9424</orcidid><orcidid>https://orcid.org/0000-0002-3281-5840</orcidid><orcidid>https://orcid.org/0000-0002-2549-3353</orcidid><orcidid>https://orcid.org/0000-0002-9295-8819</orcidid></search><sort><creationdate>20230901</creationdate><title>Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings</title><author>Ortiz-Morales, Oscar ; Ramírez-Bribiesca, J. Efrén ; Hernández-Bautista, Jorge ; Hernández-Sánchez, David ; Bárcena-Gama, José Ricardo ; Hernández-Trujillo, Elein ; Díaz-Sánchez, Victor M. ; Garrido-Fariña, German ; López-Ojeda, José C. ; Hernández-Rodriguez, Martha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>aerobiosis</topic><topic>Bioavailability</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Dosage</topic><topic>Dystrophy</topic><topic>Feed conversion</topic><topic>Food conversion</topic><topic>goat milk</topic><topic>Goats</topic><topic>growth performance</topic><topic>Histopathology</topic><topic>Hydrogen peroxide</topic><topic>Kidneys</topic><topic>Lesions</topic><topic>Life Sciences</topic><topic>Liver</topic><topic>Meat</topic><topic>Metabolism</topic><topic>Milk</topic><topic>Muscular dystrophy</topic><topic>Neonates</topic><topic>Nutrition</topic><topic>Oncology</topic><topic>Oral administration</topic><topic>Oxidative metabolism</topic><topic>Selenium</topic><topic>Selenomethionine</topic><topic>Sodium</topic><topic>Sodium selenite</topic><topic>Tissue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ortiz-Morales, Oscar</creatorcontrib><creatorcontrib>Ramírez-Bribiesca, J. Efrén</creatorcontrib><creatorcontrib>Hernández-Bautista, Jorge</creatorcontrib><creatorcontrib>Hernández-Sánchez, David</creatorcontrib><creatorcontrib>Bárcena-Gama, José Ricardo</creatorcontrib><creatorcontrib>Hernández-Trujillo, Elein</creatorcontrib><creatorcontrib>Díaz-Sánchez, Victor M.</creatorcontrib><creatorcontrib>Garrido-Fariña, German</creatorcontrib><creatorcontrib>López-Ojeda, José C.</creatorcontrib><creatorcontrib>Hernández-Rodriguez, Martha</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aqualine</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Earth, Atmospheric &amp; Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) 3: Aquatic Pollution &amp; Environmental Quality</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) Professional</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database (ProQuest)</collection><collection>Biological Science Database</collection><collection>Earth, Atmospheric &amp; Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ortiz-Morales, Oscar</au><au>Ramírez-Bribiesca, J. Efrén</au><au>Hernández-Bautista, Jorge</au><au>Hernández-Sánchez, David</au><au>Bárcena-Gama, José Ricardo</au><au>Hernández-Trujillo, Elein</au><au>Díaz-Sánchez, Victor M.</au><au>Garrido-Fariña, German</au><au>López-Ojeda, José C.</au><au>Hernández-Rodriguez, Martha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings</atitle><jtitle>Biological trace element research</jtitle><stitle>Biol Trace Elem Res</stitle><addtitle>Biol Trace Elem Res</addtitle><date>2023-09-01</date><risdate>2023</risdate><volume>201</volume><issue>9</issue><spage>4374</spage><epage>4388</epage><pages>4374-4388</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>Selenium (Se) is an essential element and antioxidant that catalyzes the destruction of hydrogen peroxide formed during cellular oxidative metabolism. Doses of Se as selenomethionine (SeMe) by oral route are 0.1–0.3 mgSe/kg DM, while the dose by parenteral route with sodium selenite (Na 2 SeO 3 ) is 0.1 mgSe/BW. The effects of supranutritional Se supplementation on normal kids have rarely been studied. The objective of the study was to evaluate both Se sources on growth performance, Se in tissues, histopathological findings, and meat characteristics. Forty-five kids of the Pastoreña breed with 25-day age were distributed (4.7 ± 1.13 kg) in three treatments: a) control group, C: consumption with goat milk (GM: containing 0.135 mgSe/g); b) NaSe: GM plus Na 2 SeO 3 injectable, 0.25 mgSe/kg BW; c) SeMe: GM plus oral dosage, 0.3 mgSe as SeMe daily. Fifteen animals per treatment were slaughtered at 7, 14, and 21 days. Feed conversion improved ( P  &lt; 0.05) with Se supplement ( P  &lt; 0.05) at 7 and 14 days. SeMe had higher protein and fat meat content ( P  &lt; 0.05). SeMe increased Se liver at 14 and 21 days. NaSe and SeMe had higher ( P  &lt; 0.05) levels of Se kidney. SeMe-21d showed 42% mononuclear and periportal cell infiltration lesions. In conclusion, Se administered through milk in goat kids was insufficient to prevent nutritional muscular dystrophy. The supranutritional dose of 0.25 mg/kg as NaSe was sufficient to maintain the Se level in tissues. SeMe increased Se liver and kidney efficiently. Both Se sources improved the bioavailability of the mineral in kids.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>36574166</pmid><doi>10.1007/s12011-022-03528-5</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0003-2137-9315</orcidid><orcidid>https://orcid.org/0000-0002-8306-1516</orcidid><orcidid>https://orcid.org/0000-0001-7575-8180</orcidid><orcidid>https://orcid.org/0000-0002-8761-3656</orcidid><orcidid>https://orcid.org/0000-0001-7286-0382</orcidid><orcidid>https://orcid.org/0000-0001-8637-5142</orcidid><orcidid>https://orcid.org/0000-0002-0039-9424</orcidid><orcidid>https://orcid.org/0000-0002-3281-5840</orcidid><orcidid>https://orcid.org/0000-0002-2549-3353</orcidid><orcidid>https://orcid.org/0000-0002-9295-8819</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0163-4984
ispartof Biological trace element research, 2023-09, Vol.201 (9), p.4374-4388
issn 0163-4984
1559-0720
language eng
recordid cdi_proquest_miscellaneous_2758576501
source Springer Nature
subjects aerobiosis
Bioavailability
Biochemistry
Biomedical and Life Sciences
Biotechnology
Dosage
Dystrophy
Feed conversion
Food conversion
goat milk
Goats
growth performance
Histopathology
Hydrogen peroxide
Kidneys
Lesions
Life Sciences
Liver
Meat
Metabolism
Milk
Muscular dystrophy
Neonates
Nutrition
Oncology
Oral administration
Oxidative metabolism
Selenium
Selenomethionine
Sodium
Sodium selenite
Tissue
title Effect of Supranutritional Dosage Selenium in Neonatal Goat Kids on Productive Performance, Physicochemical Profiles in Meat, Selenium Levels in Tissues, and Histopathological Findings
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T01%3A38%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Supranutritional%20Dosage%20Selenium%20in%20Neonatal%20Goat%20Kids%20on%20Productive%20Performance,%20Physicochemical%20Profiles%20in%20Meat,%20Selenium%20Levels%20in%20Tissues,%20and%20Histopathological%20Findings&rft.jtitle=Biological%20trace%20element%20research&rft.au=Ortiz-Morales,%20Oscar&rft.date=2023-09-01&rft.volume=201&rft.issue=9&rft.spage=4374&rft.epage=4388&rft.pages=4374-4388&rft.issn=0163-4984&rft.eissn=1559-0720&rft_id=info:doi/10.1007/s12011-022-03528-5&rft_dat=%3Cproquest_cross%3E2838106734%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c408t-26edc9464cfcf58ae7e16aa976444b6c836d6fa0be6867c5eb16c53f62d61f43%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2838106734&rft_id=info:pmid/36574166&rfr_iscdi=true