Prognostic factors in patients in the terminal phase of haematological malignancies who are receiving home medical care

Summary Although there are many prognostic models for patients in the terminal phase of solid tumours, a reliable prognostic scoring system in patients in the terminal phase of haematological malignancies (HM) has not been established. We retrospectively evaluated 180 patients in the terminal phase...

Full description

Saved in:
Bibliographic Details
Published in:British journal of haematology 2023-04, Vol.201 (2), p.290-301
Main Authors: Miyashita, Naohiro, Ohashi, Kota, Fujita, Mariko, Hosoda, Toru, Kawasaki, Yasufumi, Takimoto, Madoka, Onozawa, Masahiro
Format: Article
Language:English
Subjects:
Appetite loss
Cell number
Dyspnea
haematological malignancies
Hematologic Neoplasms - therapy
Hematology
home medical care
Humans
Japan palliative haematological oncology prognostic estimates
JPHOPE
L-Lactate dehydrogenase
Leukocytes (neutrophilic)
Lymphocytes
Malignancy
Medical prognosis
Neoplasms
Prognosis
prognostic factors
quality of life
Respiration
Retrospective Studies
Risk Factors
Risk groups
Solid tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Although there are many prognostic models for patients in the terminal phase of solid tumours, a reliable prognostic scoring system in patients in the terminal phase of haematological malignancies (HM) has not been established. We retrospectively evaluated 180 patients in the terminal phase of HM who were receiving home medical care (HMC). Multivariate analyses revealed that clinician's estimate, consciousness, loss of appetite, dyspnoea, neutrophil count, lymphocyte count, and lactate dehydrogenase were associated with overall survival (OS). Based on this result, we developed a novel prognostic scoring system, the Japan palliative haematological oncology prognostic estimates, in which four risk groups were shown to clearly differ in survival (p 
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.18623